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- W2367579730 abstract "Objective To detect IL-17 expression in lesions of oral lichen planus. Methods Tissue homogenate liquids were obtained from 26 OLP biopsy specimens and 6 controls. The expression of IL-17 was quantitated by ELISA and the total protein concentration were detected by BCA total protein detection according to the manufacturer′ s instructions. The relative amount of IL-17 was calculated as the ratio of cytokine concentration to total protein. The expression and location of IL-17 was detected by immunohistochemistry. Results IL-17 could be detected in both experimental group and control group. The relative amount of IL-17 ranged widly, and the data did not normally distributed. IL-17 was detected at extremely high levels in some OLP specimens, however, when compared with that in normal buccal mucosal tissues, no significant difference was found. The IL-17 positive cells were found dispersedly in submucosa lamina propria of OLP, and more could be observed in erosive and vesicle lesions of OLP. The IL-17 located in cytoplasm predominantly, whereas there was some weakly positive staining in extracellular space. Conclusions Our results indicate that IL-17 positive cells distributed dispersedly in submucosa lamina propria of OLP, whereas the relative levels of IL-17 displayed no significant difference between OLP and normal tissues. The potential roles of IL-17 in OLP need to be elucidated further." @default.
- W2367579730 created "2016-06-24" @default.
- W2367579730 creator A5022248284 @default.
- W2367579730 date "2009-01-01" @default.
- W2367579730 modified "2023-09-23" @default.
- W2367579730 title "Expression of IL-17 in lesion of oral lichen planus" @default.
- W2367579730 hasPublicationYear "2009" @default.
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