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- W2367584384 abstract "Objective To investigate the protective effect of Lipo2PGE1 on the canine hepatic ischemia reperfusion injury. Methods Twenty-four male healthy dogs were randomized into three groups:shame operation group(n=8),hepatic ischemia reperfusion group(n=8),Alprostadil preconditioning group(n=8).Before the blockage of porta hepatis,after 30 min ischemia and after 60 min reperfusion,ALT,AST and TNF-α levels in serum were measuered. Results Before the blockage of porta hepatis,the levels of ALT,AST and TNF-α in the serum showed no significant difference among 3 groups.After 30 min ischemia or 60 min reperfusion,ALT,AST and TNF-α levels in the serum in Alprostadil preconditioning and hepatic ischemia reperfusion group were significantly higher than in sham operation group,and significantly lower in Alprostadil preconditioning group than in hepatic ischemia reperfusion group(P0.05). Conclusion Injection of Alprostadil prior to hepatic ischemia can protect hepatic cells from the injuryinduced by ischemia reperfusion injury." @default.
- W2367584384 created "2016-06-24" @default.
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- W2367584384 date "2010-01-01" @default.
- W2367584384 modified "2023-09-28" @default.
- W2367584384 title "Effect of Lipo2PGE1 on the canine hepatic ischemia reperfusion injury" @default.
- W2367584384 hasPublicationYear "2010" @default.
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