Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367660319> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2367660319 endingPage "261" @default.
- W2367660319 startingPage "259" @default.
- W2367660319 abstract "A simple and effective method for the separation of oxybutynin enantiomers was developed using high performance liquid chromatography with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) as the chiral mobile phase additive and a C18 reversed-phase column as the stationary phase. beta-CD and HP-beta-CD were investigated as chiral mobile phase additives separately. The results showed that oxybutynin enantiomers could not be separated when adding beta-CD in the mobile phase, but optimal resolution was obtained when using HP-beta-CD as the chiral mobile phase additive. Excellent enantioseparation was achieved with the mobile phase composed of 30 mmol/L KH2PO4-acetonitrile(80:20, v/v) mixed with 60 mmol/L HP-beta-CD at pH 4.0. The detection wavelength was set at 223 nm and the column temperature was set at 28 degrees C with a flow rate of 0.8 mL/min. Under the optimized conditions, the resolution of enantiomers was 1.54 and the limit of quantitation was 1.0 ng. Comparing with chiral stationary phase chromatography, the method was simple, economic and considerably reproducible." @default.
- W2367660319 created "2016-06-24" @default.
- W2367660319 creator A5012371144 @default.
- W2367660319 creator A5021234664 @default.
- W2367660319 creator A5039760060 @default.
- W2367660319 creator A5087104530 @default.
- W2367660319 date "2008-03-01" @default.
- W2367660319 modified "2023-09-23" @default.
- W2367660319 title "High performance liquid chromatographic separation of oxybutynin enantiomers using chiral mobile phase additive" @default.
- W2367660319 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18581864" @default.
- W2367660319 hasPublicationYear "2008" @default.
- W2367660319 type Work @default.
- W2367660319 sameAs 2367660319 @default.
- W2367660319 citedByCount "2" @default.
- W2367660319 countsByYear W23676603192015 @default.
- W2367660319 countsByYear W23676603192018 @default.
- W2367660319 crossrefType "journal-article" @default.
- W2367660319 hasAuthorship W2367660319A5012371144 @default.
- W2367660319 hasAuthorship W2367660319A5021234664 @default.
- W2367660319 hasAuthorship W2367660319A5039760060 @default.
- W2367660319 hasAuthorship W2367660319A5087104530 @default.
- W2367660319 hasConcept C113196181 @default.
- W2367660319 hasConcept C138268822 @default.
- W2367660319 hasConcept C142724271 @default.
- W2367660319 hasConcept C154945302 @default.
- W2367660319 hasConcept C16838498 @default.
- W2367660319 hasConcept C178790620 @default.
- W2367660319 hasConcept C179998833 @default.
- W2367660319 hasConcept C185592680 @default.
- W2367660319 hasConcept C199360897 @default.
- W2367660319 hasConcept C204787440 @default.
- W2367660319 hasConcept C2776174256 @default.
- W2367660319 hasConcept C2777463227 @default.
- W2367660319 hasConcept C2777844464 @default.
- W2367660319 hasConcept C2778941218 @default.
- W2367660319 hasConcept C2779433975 @default.
- W2367660319 hasConcept C41008148 @default.
- W2367660319 hasConcept C43617362 @default.
- W2367660319 hasConcept C44280652 @default.
- W2367660319 hasConcept C486523 @default.
- W2367660319 hasConcept C71240020 @default.
- W2367660319 hasConcept C71924100 @default.
- W2367660319 hasConceptScore W2367660319C113196181 @default.
- W2367660319 hasConceptScore W2367660319C138268822 @default.
- W2367660319 hasConceptScore W2367660319C142724271 @default.
- W2367660319 hasConceptScore W2367660319C154945302 @default.
- W2367660319 hasConceptScore W2367660319C16838498 @default.
- W2367660319 hasConceptScore W2367660319C178790620 @default.
- W2367660319 hasConceptScore W2367660319C179998833 @default.
- W2367660319 hasConceptScore W2367660319C185592680 @default.
- W2367660319 hasConceptScore W2367660319C199360897 @default.
- W2367660319 hasConceptScore W2367660319C204787440 @default.
- W2367660319 hasConceptScore W2367660319C2776174256 @default.
- W2367660319 hasConceptScore W2367660319C2777463227 @default.
- W2367660319 hasConceptScore W2367660319C2777844464 @default.
- W2367660319 hasConceptScore W2367660319C2778941218 @default.
- W2367660319 hasConceptScore W2367660319C2779433975 @default.
- W2367660319 hasConceptScore W2367660319C41008148 @default.
- W2367660319 hasConceptScore W2367660319C43617362 @default.
- W2367660319 hasConceptScore W2367660319C44280652 @default.
- W2367660319 hasConceptScore W2367660319C486523 @default.
- W2367660319 hasConceptScore W2367660319C71240020 @default.
- W2367660319 hasConceptScore W2367660319C71924100 @default.
- W2367660319 hasIssue "2" @default.
- W2367660319 hasLocation W23676603191 @default.
- W2367660319 hasLocation W23676603192 @default.
- W2367660319 hasOpenAccess W2367660319 @default.
- W2367660319 hasPrimaryLocation W23676603191 @default.
- W2367660319 hasRelatedWork W2111834926 @default.
- W2367660319 hasRelatedWork W2302633144 @default.
- W2367660319 hasRelatedWork W2347208958 @default.
- W2367660319 hasRelatedWork W2347388738 @default.
- W2367660319 hasRelatedWork W2348604504 @default.
- W2367660319 hasRelatedWork W2353524113 @default.
- W2367660319 hasRelatedWork W2353868358 @default.
- W2367660319 hasRelatedWork W2355047707 @default.
- W2367660319 hasRelatedWork W2358423057 @default.
- W2367660319 hasRelatedWork W2359905709 @default.
- W2367660319 hasRelatedWork W2360530366 @default.
- W2367660319 hasRelatedWork W2363961422 @default.
- W2367660319 hasRelatedWork W2369324812 @default.
- W2367660319 hasRelatedWork W2372518649 @default.
- W2367660319 hasRelatedWork W2374821078 @default.
- W2367660319 hasRelatedWork W2375731609 @default.
- W2367660319 hasRelatedWork W2377751700 @default.
- W2367660319 hasRelatedWork W2378950237 @default.
- W2367660319 hasRelatedWork W2389731756 @default.
- W2367660319 hasRelatedWork W2392874991 @default.
- W2367660319 hasVolume "26" @default.
- W2367660319 isParatext "false" @default.
- W2367660319 isRetracted "false" @default.
- W2367660319 magId "2367660319" @default.
- W2367660319 workType "article" @default.