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- W2367687470 abstract "Objective To establish a ion chromatography method for the determination of residual N-methylpyrrolidine in cefepime hydrochloride/L-Arginine. Methods The determination was performed on a Metrosep C2-100 column (10 cm×4 mm×7 um). The mobile phase was a mixture of 3 mmol/L HNO3-acetonitrile (30 ∶ 70). The flow rate was 1.0 ml/min. A conductivity detector was used. Results The standard curve was linear over the range of 1.00~30.04 ug/ml (r=0.99995). The detection limit for N-methylpyrrolidine was 0.19 ug/ml. The average recovery was 94.0% (RSD=1.8%, n = 9). Conclusion The method is simple, accurate, and suitable for the determination of residual N-methylpyrrolidine in Cefepine hydrochloride/L-Arginine." @default.
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- W2367687470 date "2008-01-01" @default.
- W2367687470 modified "2023-09-25" @default.
- W2367687470 title "Determination of N-methylpyrrolidine in Cefepime Hydrochloride/L-Arginine by Ion Chromatography" @default.
- W2367687470 hasPublicationYear "2008" @default.
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