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- W2367691787 abstract "Objective:To study the endothelial dysfun ct ion in hypercholesterolemic patients and the interventional effect of Fluvastain .Methods:Applying high resolved echocardiography,we detected t he endothelial function in untreated hypercholesterolemic patients. The endothel ial function was expressed as the rate of flow-mediated dilation (Endothelium de pendent dilation,EDD).Forty-five patients who had impaired EDD were enrolled in this study.They were divided into three groups:hypercholesterolemic group (Group HC)、hypercholesterolemic patients receiving Fluvastain 20 mg·d -1 for 4 weeks(Group Flu)and hypercholesterolemic patients receiving Simvastatin 20 mg·d -1 for 4 weeks (Group Sim).Both the level of plasma cholesterol and EDD we re studied. The above results were compared with those who had normal level of p lasma lipid and normal EDD (Group NC).Results:EDDs in differen t groups at the beginning of the study were as follows:Croup NC(13.22±4.10)%, Group HC(4.16±1.37)%,Group Flu (4.20±1.4)%,Group Sim ( 4.18±1.42)%;ED Ds in different groups at the end of the study were as follows:Grou NC( 12.97± 4.11)%,Group HC(4.64±2.09)%,Group Flu (12.54±3.31)%,Group Sim ( 12.70±4.19 )%;Serum levels of cholesterol in Group Flu and Group Sim at the end of the st udy decreased significantly.[" @default.
- W2367691787 created "2016-06-24" @default.
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- W2367691787 date "2005-01-01" @default.
- W2367691787 modified "2023-09-24" @default.
- W2367691787 title "Fluvastatin Interventional Effect in Hypercholesteroemic Endothelial Dysfunction" @default.
- W2367691787 hasPublicationYear "2005" @default.
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