Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367701516> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W2367701516 abstract "Objective To investigate the changes of nitric oxide synthase (NOS) - nitric oxide (NO) system in vascular smooth muscle cells (VSMC) of patients with essential hypertension (EH), and role of these changes in the pathogenesis of hypertension. Methods The VSMC of EH patients and normotensives (NT) were cultured. The NO contents and NOS activities of the VSMC in the EH and NT groups were measured, and the characteristics of NO and NOS secretion from VSMC were observed. Results (1) The NO content and NOS activity of VSMC in the EH group were (42.73±6.76) μmol/(2.5×10~6 cells) and (0.24±0.05) nmol/(2.5×10~6 cells) respectively,significantly lower than (74.52± 4.73) μmol/(2.5 ×10~6 cells) and (0.55±0.10) nmol/(2.5 ×10~6 cells) in the NT group ( P 0.01). (2)The NO concentration and activity of NOS in VSMC of both groups increased with increasing cultivation time. (3)The concentration of NO in the two groups increased with the increasing activity of NOS,and there was a positive correlation between the NO concentration and the NOS activity. Conclusions The NOS-NO system in patients with EH is probably abnormal in structure or function,and is involved in the production and development of essential hypertension." @default.
- W2367701516 created "2016-06-24" @default.
- W2367701516 creator A5068339381 @default.
- W2367701516 date "2003-01-01" @default.
- W2367701516 modified "2023-09-25" @default.
- W2367701516 title "Changes of NOS-NO system in vascular smooth muscle cells and pathogenesis of hypertension" @default.
- W2367701516 hasPublicationYear "2003" @default.
- W2367701516 type Work @default.
- W2367701516 sameAs 2367701516 @default.
- W2367701516 citedByCount "0" @default.
- W2367701516 crossrefType "journal-article" @default.
- W2367701516 hasAuthorship W2367701516A5068339381 @default.
- W2367701516 hasConcept C126322002 @default.
- W2367701516 hasConcept C134018914 @default.
- W2367701516 hasConcept C185592680 @default.
- W2367701516 hasConcept C2777097880 @default.
- W2367701516 hasConcept C2777622882 @default.
- W2367701516 hasConcept C2779395532 @default.
- W2367701516 hasConcept C2780942790 @default.
- W2367701516 hasConcept C2992686903 @default.
- W2367701516 hasConcept C519581460 @default.
- W2367701516 hasConcept C71924100 @default.
- W2367701516 hasConcept C84393581 @default.
- W2367701516 hasConceptScore W2367701516C126322002 @default.
- W2367701516 hasConceptScore W2367701516C134018914 @default.
- W2367701516 hasConceptScore W2367701516C185592680 @default.
- W2367701516 hasConceptScore W2367701516C2777097880 @default.
- W2367701516 hasConceptScore W2367701516C2777622882 @default.
- W2367701516 hasConceptScore W2367701516C2779395532 @default.
- W2367701516 hasConceptScore W2367701516C2780942790 @default.
- W2367701516 hasConceptScore W2367701516C2992686903 @default.
- W2367701516 hasConceptScore W2367701516C519581460 @default.
- W2367701516 hasConceptScore W2367701516C71924100 @default.
- W2367701516 hasConceptScore W2367701516C84393581 @default.
- W2367701516 hasLocation W23677015161 @default.
- W2367701516 hasOpenAccess W2367701516 @default.
- W2367701516 hasPrimaryLocation W23677015161 @default.
- W2367701516 hasRelatedWork W1972653373 @default.
- W2367701516 hasRelatedWork W1976520366 @default.
- W2367701516 hasRelatedWork W1987304319 @default.
- W2367701516 hasRelatedWork W2003410167 @default.
- W2367701516 hasRelatedWork W2003465691 @default.
- W2367701516 hasRelatedWork W2017976839 @default.
- W2367701516 hasRelatedWork W2047324416 @default.
- W2367701516 hasRelatedWork W2083037047 @default.
- W2367701516 hasRelatedWork W2091074134 @default.
- W2367701516 hasRelatedWork W2094600963 @default.
- W2367701516 hasRelatedWork W2103754621 @default.
- W2367701516 hasRelatedWork W2321127082 @default.
- W2367701516 hasRelatedWork W2355773181 @default.
- W2367701516 hasRelatedWork W2364673537 @default.
- W2367701516 hasRelatedWork W2365794065 @default.
- W2367701516 hasRelatedWork W2368686148 @default.
- W2367701516 hasRelatedWork W2372693105 @default.
- W2367701516 hasRelatedWork W2376811467 @default.
- W2367701516 hasRelatedWork W2381621840 @default.
- W2367701516 hasRelatedWork W2394406379 @default.
- W2367701516 isParatext "false" @default.
- W2367701516 isRetracted "false" @default.
- W2367701516 magId "2367701516" @default.
- W2367701516 workType "article" @default.