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- W2367710052 abstract "13 C NMR spectroscopic techniques. The synthesized compounds were screened for i n vivo analgesic activity at a dose of 20 mg/kg body weight. Among them, compounds 6aP, 6aM, 6cM, 6iM and 6jM exhibited significant analgesic activity and compounds 6cM, 6iM and 6jM exhibited highly significant activity comparable with standard drug Diclofenac sodium using acetic acid)induced writhing model. Compounds 6aP, 6aM, 6cM, 6iM and 6jM were further evaluated for acute)ulcerogenesis activity. Among them, compound 6cM and 6iM were found to be most promising analgesic agent devoid of ulcerogenic effects." @default.
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- W2367710052 date "2011-01-01" @default.
- W2367710052 modified "2023-09-24" @default.
- W2367710052 title "SYNTHESIS OF NOVEL PYRIMIDINE DERIVATIVE AND ITS BIOLOGICAL EVALUATION" @default.
- W2367710052 hasPublicationYear "2011" @default.
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