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- W2367711471 abstract "Objective To compare the effects of sodium nitroprussid(SNP), SNP-perdipine and perdipine on the controlled hypotension. Methods Forty-five patients with intracranial aneurysms, whoes conditons were Hunt-Hess O～II , were randomly divided into three groups. The endovascular treatment was performed under the conscious sedation induced whith intravenous infusion of propofol in all the patieats of three growps. The controlled hypotension was induced respectively by intravenous infusion of SNP, SNP-perdipine and perdipine in the tree groups during the endovascular treatment. The radial artery pressure and mean arterial pressure the( MAP)of dorsal artery of the left foot, heart rate, ECG, saturaion of blood oxygen, the arterial blood gas analysis and blood lactic acid were monitored before, after and during the controlled hypotension. Results SNP induced the controlled hypotension faster and better than perdipine did. However it was difficult for anesthetist to observe the patient's condition and the speed of administration of SNP was necessitously adjusted at initial stage of hypotension in radioactivity environment when the controlled hypotension was induced by SNP. The MAP rised slowlier after the hypotension induced by perdipine than that by SNP. The hypotension induced by intravenous SNP-perdipine was better and more controllable than that by SNP or perdipine. Conclusions THe effect of SNP-perdipine on the controlled hypotension better and more controllable , and the frequency of adjusting the speed of administration was decreased in the radioactivity environment. Intravenous infusion of SNP-perdipine was better than SNP and perdipine for the controlled hypotension in the patients undergoing endovascular treatment." @default.
- W2367711471 created "2016-06-24" @default.
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- W2367711471 date "2005-01-01" @default.
- W2367711471 modified "2023-09-24" @default.
- W2367711471 title "Study of Effects of Sodium Nitroprusside, Sodium Nitroprusside-perdipine and Perdipine on controlled Hypotension during Endovascular Treatment in Patients with Intracranial Anevrysms" @default.
- W2367711471 hasPublicationYear "2005" @default.
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