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- W2367713318 abstract "Objective:By observing the external growth and hyperplasia of A-NK cells and the ability of killing tumor cells,to study the functions of internal anti-tumor by local injection of A-NK cells.Methods:To use Lymphocytes separation medium to separate the single nuclear cell(PBMC),to develope LAK cells,A-NK cells and then inoculate respectively the LAK cells,the A-NK cells and Walker-256 cells on culture boards for 24 hours,use the measurement of MTT to determine the absorbance and figure out its kill probability of tumor.Copy the models of rat liver cancer,respectively inject LAK,A-NK into them through arteria hepatica to observe the survival time of the two groups of the animals.Results:The hyperplasia of A-NK cells were obviously faster than that of LAK cells (P0.05`),the kill activity of A-NK cells were stronger than that of LAK cells(P0.01),and A-NK cells can obviously prolong the life span of the model of the liver cancer animals,compare with the LAK cells,it had significant difference(P0.01).Conclusion:A-NK cells have the characteristic of hyperplasia quickly,anti-tumor activity strongly,it can restrain the growth of the tumor in the body and prolong the existence period of the tumor-bearing animals." @default.
- W2367713318 created "2016-06-24" @default.
- W2367713318 creator A5082155022 @default.
- W2367713318 date "2008-01-01" @default.
- W2367713318 modified "2023-09-23" @default.
- W2367713318 title "The experimental research on local application of A-NK cells in anti-tumor" @default.
- W2367713318 hasPublicationYear "2008" @default.
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