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- W2367719602 abstract "Objective To study the expressions of bcl-2 and Bax protein after liver injury induced by intestinal ischemia-reperfusion and the effect of Astragalus membranaceus injec tions.MethodsThe model of liver injury induced by intestinal ischemi a-reperfusion was established by blocking the superior mesenteric artery with c lap.The immunohistochemistry and MIPS were used to measure bcl-2 and Bax protei n positive expression indexes in rats hepatic sham-operated group,model grou p,Astragalus membranaceus injections group.Results①bcl-2 and Bax protein positive expression indexes in m odel group were higher than those in sham-operated group,( P 0.01).②bcl-2 p rotein positive expression index in Astragalus membranaceus injections group was higher than that in model group,( P 0.01);Bax protein positive expression i ndex in Astragalus membranaceus injections group was lower than that in model gr oup ( P 0.01);ConclusionExpressions of bcl-2 and Bax prot e in increase after liver injury induced by intestinal ischemia-reperfusion in r ats;Astragalus membranaceus injections can enhance the expression of bcl-2 protein and reduce the expression of Bax protein.It may be one of mechanism s of Astragalus membranaceus injections to protect liver injury induced by inte stinal ischemia-reperfusion in rats." @default.
- W2367719602 created "2016-06-24" @default.
- W2367719602 creator A5074040616 @default.
- W2367719602 date "2003-01-01" @default.
- W2367719602 modified "2023-09-25" @default.
- W2367719602 title "Experimental study on the effect of Astragalus Membranaceus In jection on the expression of bcl-2 and Bax protein after liver injury induced by intestinal ischemia-reperfusion i n rats" @default.
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