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- W2367722768 abstract "Objective To evaluate the efficacy and safety of voluven ( hydroxyethyl starch 130/0.4 ) for fluid resuscitation in Chronic obstructive pulmonary disease(COPD) patients. Methods Forty tracheal intubated, mechanically ventilated COPD patients with blood pressure dropping were randomly divided into voluven group (20 patients) and Ringer solution group (20 patients ). The time taken to achieve cardiovascular stability, the resuscitative fluid volume, hemorheology, blood coagulation, renal function and adverse events were monitored. Results For voluven and Ringer solution, the fluid volume was (1535±380)ml and (2150±427)ml and the resuscitative time was (5.21±1.94)h and ( 6.48 ±2.36)h respectively (P0.05). The hemorheology parameters were improved in voluven (P 0.01 ), but not in Ringer solution (P 0.05 ). Blood coagulation and renal function were not changed after fluid resuscitation(P0.05). The edema of lower extremity was worse in 3 patients of Ringer solution group. Conclusion Voluven could effectively and quickly maintain hemodynamic stability, improve the hemorheological status. It may improve organ perfusion and tissue oxygenation. Voluven should be considered firstly for fluid resuscitation in COPD patients." @default.
- W2367722768 created "2016-06-24" @default.
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- W2367722768 date "2006-01-01" @default.
- W2367722768 modified "2023-09-23" @default.
- W2367722768 title "The clinical research of voluven for fluid resuscitation in Chronic obstructive pulmonary disease patients" @default.
- W2367722768 hasPublicationYear "2006" @default.
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