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- W2367723982 abstract "Objective To determine the relationship between hemoglobin variability and mortality in maintenance hemodialysis(MHD) patients. Methods A total of 364 MHD cases were recruited from Shang- hai Renal Registry Network. The relationship between hemoglobin variability and all-cause mortality was as- sessed. Results In the 364 MHD cases, the average age was 63.07 ± 13.93 years, the dialysis vintage was 76.0(42.25, 134.0) months, and 85 patients(23%) died. The dead patients had a higher mean hemoglobin SD and CV comparing with the survival patients(19.19±6.31 vs. 13.74±5.89, and 0.172±0.07 vs. 0.126±0.056, re- spectively, P0.001). Risk of all- cause mortality in patients in the upper quartile(P75) of hemoglobin SD was significantly higher than those in the lower quartile(P25)(OR=5.964, 95% CI 2.663~13.357, P0.001), even after adjustment for demographic data, lifestyle factors and biochemical markers(OR=4.961, 95% CI 1.959~11.238, P0.001). Kaplan-Meier method showed that patients with hemoglobin SD and CV in the up- per quartile had a lower survival rate(P0.001). ROC-AUC of hemoglobin SD and CV for all-cause mortali- ty were 0.677 and 0.721, respectively(cutoff 10.647g/l and 0.1086, respectively; accuracy 89.4% and 85.1%, respectively; specificity 67.7% and 60.3%, respectively; P0.001). Multivariate logistic regression analysis showed that higher hemoglobin CV, older age and higher CRP were the independent risk factors for all-cause mortality. Conclusions The highest hemoglobin SD and CV were independently correlated with all- cause mortality. Hemoglobin variability may have prediction value for mortality in MHD patients." @default.
- W2367723982 created "2016-06-24" @default.
- W2367723982 creator A5078400238 @default.
- W2367723982 date "2014-01-01" @default.
- W2367723982 modified "2023-09-26" @default.
- W2367723982 title "Hemoglobin variability is associated with mortality in patients on maintenance hemodialysis" @default.
- W2367723982 hasPublicationYear "2014" @default.
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