Matches in SemOpenAlex for { <https://semopenalex.org/work/W2367728336> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2367728336 abstract "Objective:To investigate the effects of curcumin on the cartilage in knee joint osteoarthritis of rabbits.Methods:Rabbits were randomly divided into control (A)group, curcumin (B)group and osteoarthritis (C)group.Except(A)group, the other two groups were established the model of the osteoarthritis with papain, Each group involved ten rabbits.The rabbits in group B was treated by 5% curcumin 9mg/(kg.week), and the rabbits in A and C group were treated by Sodium Chloride 0.5ml.Reverse transcription-polymerase chain reaction (RT-PCR) was used to detecte the expressions of CL-2, Mmp9, COX-2, IKKβ, NF-Кb.Tunel was used to measure the chondrocyte apoptosis condition.Results:After four weeks treatment, the expressions of CL-2 in group B is higher than that in group C, but the expression of Mmp9, COX-2, IKKβ, NF-Кb is lower than that in osteoarthritis group (P0.05).The expressions of CL-2 in group B and C were lower than that in group A (P0.05), but expressions of Mmp9, COX-2, IKKβ, NF-Кb was higher than that in group A(P0.05).There was statistical significance for the chondrocyte apoptdtic index(AI)between group B and C.Conclusion:The injection of 5% curcumin solution into the knee joints of the rabbits with osteoarthritis can decrease the degeneration of the cartilage duing to the Suppression of the two IL-1β/IKKβ/NF-Кb/ COX-2, Mmp9 signaling pathways" @default.
- W2367728336 created "2016-06-24" @default.
- W2367728336 creator A5079543029 @default.
- W2367728336 date "2010-01-01" @default.
- W2367728336 modified "2023-09-28" @default.
- W2367728336 title "Effects of curcumin on expressions of CL-2,Mmp9,cox-2,IKKβ,NF-Кb and tissue changes in the cartilage in knee joint osteoarthritis of rabbit" @default.
- W2367728336 hasPublicationYear "2010" @default.
- W2367728336 type Work @default.
- W2367728336 sameAs 2367728336 @default.
- W2367728336 citedByCount "0" @default.
- W2367728336 crossrefType "journal-article" @default.
- W2367728336 hasAuthorship W2367728336A5079543029 @default.
- W2367728336 hasConcept C100175707 @default.
- W2367728336 hasConcept C104317684 @default.
- W2367728336 hasConcept C105580179 @default.
- W2367728336 hasConcept C105702510 @default.
- W2367728336 hasConcept C126322002 @default.
- W2367728336 hasConcept C127561419 @default.
- W2367728336 hasConcept C134018914 @default.
- W2367728336 hasConcept C142724271 @default.
- W2367728336 hasConcept C185592680 @default.
- W2367728336 hasConcept C190283241 @default.
- W2367728336 hasConcept C204787440 @default.
- W2367728336 hasConcept C2775997469 @default.
- W2367728336 hasConcept C2776164576 @default.
- W2367728336 hasConcept C2777730290 @default.
- W2367728336 hasConcept C2777785397 @default.
- W2367728336 hasConcept C2778250585 @default.
- W2367728336 hasConcept C2779730028 @default.
- W2367728336 hasConcept C2780550940 @default.
- W2367728336 hasConcept C2780678043 @default.
- W2367728336 hasConcept C2781403057 @default.
- W2367728336 hasConcept C4692481 @default.
- W2367728336 hasConcept C55493867 @default.
- W2367728336 hasConcept C71924100 @default.
- W2367728336 hasConcept C98274493 @default.
- W2367728336 hasConceptScore W2367728336C100175707 @default.
- W2367728336 hasConceptScore W2367728336C104317684 @default.
- W2367728336 hasConceptScore W2367728336C105580179 @default.
- W2367728336 hasConceptScore W2367728336C105702510 @default.
- W2367728336 hasConceptScore W2367728336C126322002 @default.
- W2367728336 hasConceptScore W2367728336C127561419 @default.
- W2367728336 hasConceptScore W2367728336C134018914 @default.
- W2367728336 hasConceptScore W2367728336C142724271 @default.
- W2367728336 hasConceptScore W2367728336C185592680 @default.
- W2367728336 hasConceptScore W2367728336C190283241 @default.
- W2367728336 hasConceptScore W2367728336C204787440 @default.
- W2367728336 hasConceptScore W2367728336C2775997469 @default.
- W2367728336 hasConceptScore W2367728336C2776164576 @default.
- W2367728336 hasConceptScore W2367728336C2777730290 @default.
- W2367728336 hasConceptScore W2367728336C2777785397 @default.
- W2367728336 hasConceptScore W2367728336C2778250585 @default.
- W2367728336 hasConceptScore W2367728336C2779730028 @default.
- W2367728336 hasConceptScore W2367728336C2780550940 @default.
- W2367728336 hasConceptScore W2367728336C2780678043 @default.
- W2367728336 hasConceptScore W2367728336C2781403057 @default.
- W2367728336 hasConceptScore W2367728336C4692481 @default.
- W2367728336 hasConceptScore W2367728336C55493867 @default.
- W2367728336 hasConceptScore W2367728336C71924100 @default.
- W2367728336 hasConceptScore W2367728336C98274493 @default.
- W2367728336 hasLocation W23677283361 @default.
- W2367728336 hasOpenAccess W2367728336 @default.
- W2367728336 hasPrimaryLocation W23677283361 @default.
- W2367728336 hasRelatedWork W2259903613 @default.
- W2367728336 hasRelatedWork W2347289558 @default.
- W2367728336 hasRelatedWork W2349116818 @default.
- W2367728336 hasRelatedWork W2362018571 @default.
- W2367728336 hasRelatedWork W2370124045 @default.
- W2367728336 hasRelatedWork W2373755186 @default.
- W2367728336 hasRelatedWork W2375104194 @default.
- W2367728336 hasRelatedWork W2376160196 @default.
- W2367728336 hasRelatedWork W2393478867 @default.
- W2367728336 hasRelatedWork W2404330354 @default.
- W2367728336 hasRelatedWork W2409905031 @default.
- W2367728336 hasRelatedWork W2412196339 @default.
- W2367728336 hasRelatedWork W2984237372 @default.
- W2367728336 hasRelatedWork W2990354324 @default.
- W2367728336 hasRelatedWork W3025525831 @default.
- W2367728336 hasRelatedWork W3029701054 @default.
- W2367728336 hasRelatedWork W3030417717 @default.
- W2367728336 hasRelatedWork W3031520985 @default.
- W2367728336 hasRelatedWork W3043768045 @default.
- W2367728336 hasRelatedWork W3149147465 @default.
- W2367728336 isParatext "false" @default.
- W2367728336 isRetracted "false" @default.
- W2367728336 magId "2367728336" @default.
- W2367728336 workType "article" @default.