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- W2367788250 abstract "Objective: To observe the effect of herbs-partition moxibustion on expressions of MyD88 and TRAF6 in colon of UC rats,and explore the responsive mechanism of Herbs-partition moxibustion on UC. Methods: The ulcerative colitis model was established by immunological and local stimulating methods. The affirmed rats models were randomly divided into four groups: normal control( NC,n = 10),model control( MC,n = 10),herbs-partition moxibustion( HPM,n =10),and Sulfasalazine( SASP,n = 10). Scores of colon appearance and histopathology( HP) were evaluated after therapeutic interventions eight days. Immunohistochemistry analysis was used to evaluate expressions of MyD88 and TRAF6 in tissue of colon. Results: The scores of colon appearance and histopathology were decreased significantly in HPM and SASP compared with MC( P 0. 01). The expressions of MyD88 and TRAF6 of colonic tissue in MC were increased significantly compared with NC( P 0. 01),while expressions of these were decreased significantly compared with MC after therapeutic interventions( P 0. 01). Conclusion: These results demonstrated that one of responsive mechanisms of herbs-partition moxibustion on UC was to regulate the expressions of MyD88 and TRAF6 in signal pathway of TRL / MyD88 / NF-κB." @default.
- W2367788250 created "2016-06-24" @default.
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- W2367788250 date "2013-01-01" @default.
- W2367788250 modified "2023-09-23" @default.
- W2367788250 title "Effect of Herbs-partition Moxibustion on Expressions of MyD88 and TRAF6 in Colon of UC Rats" @default.
- W2367788250 hasPublicationYear "2013" @default.
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