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- W2367793595 abstract "[Objective]To analyze the genetic correlation of Vibrio cholera came from different source during the same cholera outbreak,and trace back its source,so as to provide a basis for infections source control.[Methods]39 strains of Vibrio cholera isolated on the basis of route aetiological method were detected the cholera toxin(CT)and Zonula occludens toxin(ZOT)by PCR,and the genotypes of strains were determined by ribotypes(RT),and the DNA fragments of strains were analyzed by pulse field gel electrophoresis(PFGE),followed by clustering.[Results]During two cholera outbreaks,the results of diagnostic serum and bacteriophage-biotype of strains isolated in the outbreaks were different,and CT and ZOT were negative,pattern of PFGE and RT showed the same quantity and the same molecular weight. Patterns of PFGE and RT in the two outbreaks showed to be basically the same,while different from those of strains in sporadic cholerae outbreaks.[Conclusion]PFGE and RT were helpful for determine the heredity background of Vibrio cholera strains and the infectious resource of the outbreak,which could help to effectively control the spread of cholera." @default.
- W2367793595 created "2016-06-24" @default.
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- W2367793595 date "2008-01-01" @default.
- W2367793595 modified "2023-09-25" @default.
- W2367793595 title "APPLICATON OF RIBOTYPE AND PULSE FIELD GEL ELECTROPHORESIS IN CHOLERA EPIDEMIC SITUATION" @default.
- W2367793595 hasPublicationYear "2008" @default.
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