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- W2367897310 abstract "Objective To explore the effect of low molecular weight heparin( LMWH) on adhesion and migration of hepatocellular carcinoma cell lines HepG2. Methods The different concentration LMWH were added in HepG2cells;then the migration and adhesion of HepG2 cells were examined by Transwell and fibronectin protein test respectively at 24,48 and 72 hours after the LMWH were added in HepG2 cells. Results There was no statistic difference of cell growth inhibition rate in0. 0 × 106IU·L- 1group among 24,48 and 72 hours(P 0. 05);there were statistic differences of cell growth inhibition rates in 0. 5 × 106,1.0 ×106,1.5 ×106,2.0 ×106,2.5 ×106IU·L- 1group among 24,48 and 72 hours(P 0. 05). There were statistic differences of cell growth inhibition rates between 0. 0 × 106IU·L- 1group and 0. 5 × 106,1. 0 ×106,1. 5 ×106,2. 0 × 106,2.5 ×106IU·L- 1group(P 0. 05);there were statistic differences of cell growth inhibition rates between 2. 0,2. 5 × 106IU·L- 1group and 0. 5 × 106IU·L- 1group(P 0. 05);there was no statistic difference of cell growth inhibition rate among other concenthation groups(P 0. 05). Compared with the blank control group,the migration and adherence rates in 0. 5,5. 0 and 10. 0 g·L- 1group were decreased significantly( P 0. 05);there were statistic differences of the migration and adherence rates among 0. 5,5. 0 and 10. 0 g·L- 1group(P 0. 05). Conclusion LMWH can inhibit the growth of cells,and reduce the migration and adherence rates of HepG2 cells." @default.
- W2367897310 created "2016-06-24" @default.
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- W2367897310 date "2014-01-01" @default.
- W2367897310 modified "2023-09-27" @default.
- W2367897310 title "Effect of low molecular weight heparin on the migration and adherence of hepatocellular carcinoma cell lines HepG_2" @default.
- W2367897310 hasPublicationYear "2014" @default.
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