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- W2367939753 abstract "Objective: To establish the rabbit model of acute lung injury (ALI) by intratracheal instillation of Escherichia coli , and to study the pathogenesis of bacteria-induced ALI. Methods:Nineteen New Zealand rabbits were divided into 3 groups: group 1 (intratracheally instilled Escherichia coli ), group 2 (intratracheally instilled saline), and group 3 (control group). The indexes, including hemodynamics, respiratory mechanics, blood-gas analysis, cell count in bronchial lavage fluid, protein content, lung wet-to-dry weight ratio, and pathological examination, were determined in these 3 groups. Results:There were significant differences in the above indexes both between group 1 and group 2 and between group 1 and group 3 (both P 0.05). Conclusion:ALI model can be established by intratracheal instillation of Escherichia coli ." @default.
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- W2367939753 date "2006-01-01" @default.
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- W2367939753 title "Acute lung injury induced by intratracheal instillation of Escherichia coli in rabbits" @default.
- W2367939753 hasPublicationYear "2006" @default.
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