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- W2367993034 abstract "Objective To determine allelic association of the Taq I polymorphisms for the manganese superoxide dismutase (MnSOD/SOD 2) gene with schizophrenia in Indian.Method SOD 2 gene allelic frequency and genotype were examined with the methods of the polymerase chain reaction (PCR) and restrictive fragment length polymorphism (RFLP) analysis in samples of 68 unrelated patients with schizophrenia and 62 unrelated population?based case controls.Results Taq I digestion of the PCR fragments showed two ploymorphic sites named site A and site B.The frequencies of the two Taq I polymorphic sites did not show significant difference between the subjects. But schizophrenic patients showed excess B 2B 2 homozygotic genotype as compared with normal control subjects.Conclusion Whether or not allelic association of the Taq I polymorphism for SOD 2 gene is with schizophrenia needs to be replicated with an independent study to rule out a false positive result caused by the population structure." @default.
- W2367993034 created "2016-06-24" @default.
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- W2367993034 date "2000-01-01" @default.
- W2367993034 modified "2023-09-25" @default.
- W2367993034 title "The Allelic Association of Taq I Polymorphisms for the Manganese Superoxide Dismutase Gene with Schizophrenia" @default.
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