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- W2368045197 abstract "ObjectiveTo study the antihyperlipidemia active fraction of Atractylodis Macrocephalae Rhizome(AMR) Extracts in hyperlipoidemic mice. MethodsHyperlipidemia mouse model was established with a high lipid diet,and the mice were treated with AMR and its three fractions for 4 weeks.The effects of AMR and its three fractions on body weight,serum TC TG,HDL-C,ALT and AST levels,liver and kidney coefficients were measured.The organs and urine were collected and compared. ResultsAMR 100% methanol fraction(AMRF I) significantly reduced body weight and serum TG level(P 0.05),significantly increased serum HDL-C and HDL-C/TC levels(P 0.05).AMR and AMRF I produced an obvious increase in activities of serum ALT and AST(P 0.05),and AMRF I significantly improved the liver coefficient(P 0.05). ConclusionAMRF I has a potent antihyperlipidemic effect in hyperlipidemia mice.The finding suggests that the antihyperlipidemia active components are mainly non-polar phytochemicals in AMR." @default.
- W2368045197 created "2016-06-24" @default.
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- W2368045197 date "2011-01-01" @default.
- W2368045197 modified "2023-09-23" @default.
- W2368045197 title "Antihyperlipidemia Active Fraction of Atractylodis Macrocephalae Rhizome Extracts" @default.
- W2368045197 hasPublicationYear "2011" @default.
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