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- W2368054208 abstract "Objective To explore the effects of different dosage of hydroxyapatite ceramic(HAP) Nano-particles on apoptosis of H22 tumor cell line in mice hepatic cancer.Methods 100 mice with tumor of H22 were divided into groups randomly,which taken different dosage of HPA Nano-particles in different group one time a day.After 11 days,all the mice were sacrificed and the inhibition rate and the cell apoptosis were calculated to evaluate the relationship between dosage of HAP Nano-particles and tumor growth.Results Tumor of H22 were sensitive to HAP Nano-particles,and could also prolong the life span of mice(P0.01).The results was approximate to that of mitomycin group(P0.05)。The weight of the mice did not decrease.The rate of apoptosis and that of growth inhibiting increased with the rising concentration of the HAP Nano-particles.Conclusion HAP Nano-particles can induce apoptosis of the tumor H22 cell line in mice,which is dose-dependent." @default.
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- W2368054208 date "2007-01-01" @default.
- W2368054208 modified "2023-09-23" @default.
- W2368054208 title "Effects of hydroxyapatite ceramic nano-particles on apoptosis of H22 tumor cell line of mice hepatic cancer" @default.
- W2368054208 hasPublicationYear "2007" @default.
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