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- W2368085556 abstract "Objective To study the protective role of the myocardial ischemic preconditioning(IP) on the myocardium of Cavia procellus.Methods The myocardial IP and I/R models were established by ligaturing and opening left anterior descending coronary artery in Cavia procellus.Sixty Cavia procellus were divided into three groups with each group 20 cavies(myocardial IP group,NIP group and control group).The II lead ECG was recorded continuously.The levels of serum CK-MB,IL-8 and TNF-α were determined.The MDA and Cu-Zn SOD were assessed in myocardial tissues.Results The areas of myocardial necrosis in IP and NIP groups were 40.5% and 65.8% respectively(P0.01).The ventricular arrhythmias were decreased in IP group during reperfusion period and the ventricular fibrillation arrhythmia decreased more significantly than NIP group(P0.01).The levels of serum CK-MB and TNF-α,and myocardium MDA in IP group were decreased more significantly than in NIP group(P0.05).Conclusion The myocardial IP obviously reduced the myocardial necrosis areas and the happening of the ventricular fibrillation arrhythmias in Cavia procellus during the ischemic reperfusion period as a result of decreased TNF-α and antioxidation." @default.
- W2368085556 created "2016-06-24" @default.
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- W2368085556 date "2008-01-01" @default.
- W2368085556 modified "2023-09-24" @default.
- W2368085556 title "The influence of myocardial ischemic preconditioning on the myocardium of Cavia procellus" @default.
- W2368085556 hasPublicationYear "2008" @default.
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