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- W2368100886 abstract "Objective To explore the correlation between cyclinD 1, p16 expression and the recurrence of malignant glioma after operation and radiotherapy.Methods Sixty-two cases were confirmed recurrence among the malignant glioma patients who had undergone total removal and regular radiotherapy, cyclinD 1 and p16 protein expression level were detected, binding traditional prognostic factor(sex, age, course, neoplasm size and pathological kind), Kaplan-Meier methods and the logrank test were used in tumor recurrence univariate analysis to inspect into possible differences. Cox stepwise regression model was used in multivariate analysis for tumor recurrence evaluation.Results Course of disease, tumor size, neoplasm pathology and expression of cyclinD 1 and p16 protein were demonstrated as independent factors to the recurrence of malignant glioma. Multivariate analysis showed that the expression of p16 protein and tumor pathological character could provide prognostic value of its recurrence.Conclusion The tumor cell expressed with cyclinD 1, p16 are probably related to the recurrent time of malignant glioma." @default.
- W2368100886 created "2016-06-24" @default.
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- W2368100886 date "2003-01-01" @default.
- W2368100886 modified "2023-09-28" @default.
- W2368100886 title "The study of the correlation between the expression of cyclinD_ 1 and p16 and recurrence in malignant gliomas" @default.
- W2368100886 hasPublicationYear "2003" @default.
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