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- W2368150003 abstract "Objective: To observe the protective effect of modified Yuyang Decoction on ulcerative colitis model in mice and the possible mechanism of the mucosal barrier. Methods: 40 male C57 BL /6 mice were randomly divided into normal group,model group and treatment group,10 rats in each group. The normal group and model group were given normal saline enema,the treatment group was given Chinese medicine enema and the control group was given sulfasalazine enema,14 D. Observe the body weight of rats in the groups change,disease activity index; content using fluorescence spectrophotometer to measure serum of FITC dextran. Results: In the model group,the body mass index of disease activity compared with the normal group,the difference was statistically significant(P 0. 05).Compared with the normal group,model group,the serum FITC dextran content,the difference was statistically significant(P 0. 05).But the treatment group compared with the normal group,no significant difference(P 0. 05). Conclusion: The modified Yuyang formula helps to maintain the ulcerative colitis mucosal barrier function and structure,thereby reducing the intestinal mucosal barrier permeability,tissue damage caused by the improvement of inflammation,has a good protective effect on ulcerative colitis in mice model of colon mucosal barrier." @default.
- W2368150003 created "2016-06-24" @default.
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- W2368150003 date "2015-01-01" @default.
- W2368150003 modified "2023-09-25" @default.
- W2368150003 title "Effects of Yuyang Decoction on Ulcerative Colitis in Mice Model of Mucosal Barrier" @default.
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