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- W2368201576 abstract "Objective To study the changes of important plasma indicators of secondary fibrinolytic system in patients with liver diseases,such as D-dimer(D-D) and fibrinogen(FIB),and its clinical significance.Methods ACLs-ELITEPRO automatic coagulation instrument made in USA was used to detect the FIB and D-D contents in the plasma of 35 healthy subjects and 94 cases with liver diseases.Results Compared with that in the healthy normal group,the content of FIB in the liver disease group was lower.The declining order was as follows:acute hepatitis group healthy controls chronic hepatitis liver cancer liver cirrhosis group,there was no significant difference in acute hepatitis group and chronic hepatitis group,and there were significant differences in cirrhosis group and HCC group(P0.05);the order of increase in D-D level was as follows:healthy control group the acute hepatitis group chronic hepatitis liver cancer group cirrhosis group,and the difference in each liver disease group was statistically significant.Compared with those in acute hepatitis,chronic hepatitis and cirrhosis groups,FIB and D-D contents in HCC and cirrhosis groups were significantly different.Conclusion FIB and D-D levels in plasma of patients with liver diseases can reflect objectively the severity of liver diseases.This may provide an important basis for the diagnosis,treatment and prognosis of liver diseases in clinic." @default.
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- W2368201576 date "2012-01-01" @default.
- W2368201576 modified "2023-09-28" @default.
- W2368201576 title "Significance in the Detection of Key Factors in Fibrinolytic System of Patients with Liver Diseases" @default.
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