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- W2368210523 abstract "Using silk fibroin as a co-absorbed and protective carrier,a novel method of growth factor loading in tissue engineering scaffold was developed.The influence of the growth factor loading technology to the property of gelatin porous scaffold was studied.The porosities of gelatin scaffold and SF/EGF modified scaffold were over 90%.The water uptake increased 18times after SF/EGF modification.Compressive tests showed an increase of compressive modulus at 26.1kPa after SF/EGF modification.Elisa test displayed that active EGF could be detected in 4weeks in vitro.The dose of released EGF from a milligram scaffold was in the range of 0.3-0.5ng in every time intervals and the cumulative release was 3.473ng during 28d.MTT test and SEM observation indicated that EGF loading scaffold improved the growth of epithelial cells.This growth factor loading method may be particularly useful in modification of tissue engineering scaffold." @default.
- W2368210523 created "2016-06-24" @default.
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- W2368210523 date "2014-01-01" @default.
- W2368210523 modified "2023-09-23" @default.
- W2368210523 title "Study of growth factor loading method in scaffold using silk fibroin as carrier" @default.
- W2368210523 hasPublicationYear "2014" @default.
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