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- W2368227799 abstract "Objective: To evaluate the short-term effect of thrombus aspiration catheters combining tirofiban medication for myocardial tissue reperfusion recovery in patients with acute ST-elevation myocardial infarction(STEMI).Methods: A total of 105 STEMI patients with percutaneous coronary intervention(PCI) in our hospital from 2011-05 to 2013-05 were studied, there were 73 male and 32 female with the mean age of(58.39 ± 10.37) years. The patients were randomly divided into 2 groups, Group A, the patients received thrombus aspiration catheters with intravenous tirofiban, n=53 and Group B, the patients received tirofiban and PCI, n=52. The basic clinical features, myocardial tissue perfusion level, major adverse cardiovascular events(MACE) at post operative and in-hospital period were recorded, the cardiac function was examined by echocardiography at 6 months after PCI in both groups.Results: The basic clinical features were similar between 2 groups. The thrombolysis in myocardial infarction trial(TIMI) 3 flow rate was higher in Group A than that in Group B(92.45% vs 55.77%), P=0.000. TIMI 2 and TIMI 0~1 flow rates were lower in Group A than that in Group B(7.55% vs 26.92%), P=0.008 and(0 % vs 17.31%), P=0.002. The adjusted TIMI frame was lower in Group A(27.26±5.50) vs(38.98±5.42), P0.001. The echocardiography at 6 months after PCI indicated that Group A had higher LVEF than that in Group B(0.55±0.06) vs(0.47±0.06), P0.001; lower left ventricular end diastolic diameter(50.77±5.45) vs(54.76±5.34), P0.001; less angina and target vessel revascularization(16.98% vs 40.38%), P=0.008 and(9.43% vs 17.31%), P=0.008. The incidence of MI, acute heart failure, cardiac death and non-target vessel revascularization were similar between 2 groups, P0.05.Conclusion: Thrombus aspiration catheters combining tirofiban medication may obviously improve the myocardial tissue reperfusion and the short-term cardiac function in STEMI patients after PCI, it could reduce the incidence of noreflow without increasing MACE." @default.
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- W2368227799 date "2014-01-01" @default.
- W2368227799 modified "2023-09-28" @default.
- W2368227799 title "Short-term Effect of Thrombus Aspiration Catheters Combining Tirofiban Medication for Myocardial Tissue Reperfusion Recovery in Patients With Acute ST-elevation Myocardial Infarction" @default.
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