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- W2368234019 abstract "Gene therapy,as a promising therapeutics to treat genetic or acquired diseases,has received significant attention in the past several decades due to its advantages over traditional therapies. And successful gene therapy was based on high-performance delivery system. Meanwhile,the delivery efficiencies of non-virus gene carriers were lower than that of virus. However,virus-mimic carrier constructed by self-assembly could enhance the delivery efficiency and biocompatibility,and provide effective strategy and method for gene therapy. The aim of virus-mimic carrier is to simulate the gene encapsulation and delivery model of virus by protein capsid. Further more,there are three mimic models: the first was the environmental-stimulus responsive shell-corestructure virus-mimic carrier,the second was self-assembly virus-mimic carrier,and the third was virus-mimic carrier constructed by nano particles. In this paper,the recent progress of various virus-mimic gene carrier systems was summarized and commented." @default.
- W2368234019 created "2016-06-24" @default.
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- W2368234019 date "2015-01-01" @default.
- W2368234019 modified "2023-09-24" @default.
- W2368234019 title "Advance in Research of Virus-Mimic Gene Delivery Systems" @default.
- W2368234019 hasPublicationYear "2015" @default.
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