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- W2368241331 abstract "Objective: To observe the clinical effect and untoward effect of high-dose dexamethasone and conventional prednisone for immunologic thrombocytopenic purpura( ITP). Methods: Forty-five patients with newly diagnosed ITP were divided into two groups,treatment group 20 cases,dexamethasone 40 mg / d,continuous 4 d; control group 25 patients,prednisone 1 mg·kg-1·d-1. Results: The first 4 days after treatment,platelet count were( 35 ± 18. 2) × 109/ L and( 16 ± 6. 4) ×109/ L in two groups,there was significient difference( P 0. 05). The total effective rate was 85% and 76% in treatment group and control group respectively and there is no significant difference between these two groups( P 0. 05). The long-term response rates were 52. 6 % and 31. 8% in treatment group and control group respectively and there is a significant difference between these two groups. All patients in the control group were welcomed with varying degrees library 's performance; 2 cases secondary to hyperglycemia; 3 cases of secondary infection. Compared with the control group,side effects was mild in treatment group. Conclusion: High-dose dexamethasone might be use as first-line method to treat the newly diagnosed ITP. The long-term response rates is high,adverse reactions is small,can be used as first-line clinical program." @default.
- W2368241331 created "2016-06-24" @default.
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- W2368241331 date "2014-01-01" @default.
- W2368241331 modified "2023-09-28" @default.
- W2368241331 title "The experience of high-dose dexamethasone in newly diagnosed immunologic thrombocytopenic purpura" @default.
- W2368241331 hasPublicationYear "2014" @default.
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