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- W2368246504 abstract "[Purpose] To investigate the expressions of cyclooxygenase 2(COX-2) and p53 in the patients with non-small cell lung cancer (NSCLC) and their clinical significance. [Methods] The expressions of COX-2 and p53 were detected with immunohistochemical staining in 60 cases of NSCLC. [Results] The expressions of COX-2 and p53 in NSCLC were 56.67% and 61.67%, respectively. The expression of COX-2 was correlated with pathological types (P=0.009). Median survival time(MST) and 3-year survival in stage Ⅲ patients with positive COX-2 expression were significantly lower than those with negative COX-2 expression, but median survival time and 3-year survival were not significantly different between the patients with positive or negative p53 expression. The Cox-regression analysis showed that TNM staging and COX-2 expression were independent prognostic factors in patients with NSCLC. [Conclusions] High expression of COX-2 is related with poor prognosis in NSCLC." @default.
- W2368246504 created "2016-06-24" @default.
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- W2368246504 date "2007-01-01" @default.
- W2368246504 modified "2023-09-23" @default.
- W2368246504 title "Expressions of COX-2 and p53 in Patients with Non-small Cell Lung Cancer and Their Significance" @default.
- W2368246504 hasPublicationYear "2007" @default.
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