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- W2368249192 abstract "Objective To investigate the clinical efficacy of fluticasone plus combied with bacterial lysates in treatment of children with asthma and security.Methods A randomized and controlled trial was made.Nighty-three children aged 5-12 years old with intermittent asthma were enrolled and randomly divided into two groups:the experimental group(47 cases) received fluticasone plus bacterial lysates,control group(46 cases) received fluticasone only.The episodes of respiratory tract infection and asthma,cytokine levels,immunoglobulin in serum and the adverse events were recorded in the following 12 months.Results Compared with control group,the frequencies of asthma exacerbation(t=4.758,P0.01),upper respiratory tract infection(t=10.731,P0.01),lower respiratory tract infection(z=3.548,P0.05)significantly reduced;the days of fever(t=2.401,P0.05),cough(z=3.267,P0.05),antibiotics usage(t=2.079,P0.05)significantly reduced too in the experimental group.There was significant difference in all index.Compared with control group,at the end of three months after treatment,serum IFN-γ(χ2=10.417,P0.01),serum IgA(t=5.928,P0.01) and salivary slgA(t=13.627,P0.01)significantly increased with a significate difference,while serum IL-4 decreased(χ2=6.106,P0.05) in the experimental group.There was no significantly difference in the adverse events between two groups(χ2=2.601,P0.05).Conclusion A better control was observed in children receiving inhaled fluticasone and bacterial lysates,compared to those who were treated with inhaled fluticasone only.Inhaled fluticasone plus bacterial lysates is a good choice for children with intermittent asthma." @default.
- W2368249192 created "2016-06-24" @default.
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- W2368249192 date "2011-01-01" @default.
- W2368249192 modified "2023-09-23" @default.
- W2368249192 title "Clinical Efficacy of Fluticasone Plus Combied with Bacterial Lysates in Treatment of Children with Asthma" @default.
- W2368249192 hasPublicationYear "2011" @default.
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