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- W2368310462 abstract "Objective:To obtain the genetic polymorphism data and the distribution by testing drunkenness CYP2E1 gene.Methods:The PCR-RFLP was used to analyze genetic polymorphism of CYP2E1 gene and test the genotype and gene frequencies in 154 cases.Results:Two alleles were detected in the CYP2E1 gene of 154 drunkenness samples:alleles c1 and c2,including three genotypes c1/c1、c1/c2 and c2/c2,the total of which were the 68.8%,29.2% and 1.9%,respectively.Conclusion:The results of the statistical analysis of this experiment and previous studies(alcohol dependence and healthy control group CYP2EI polymorphism)suggest:there is no different CYP2E1 gene distribution between drunkenness group and alcohol dependence group but significant difference exists when compared with the healthy control group(P0.05).The results of the statistical analysis by alcohol consumption and genotype indicate no statistical significance." @default.
- W2368310462 created "2016-06-24" @default.
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- W2368310462 date "2011-01-01" @default.
- W2368310462 modified "2023-09-27" @default.
- W2368310462 title "CYTOCHROME P4502E1 GENETIC POLYMORPHISM IN DRUNKENNESS" @default.
- W2368310462 hasPublicationYear "2011" @default.
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