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- W2368360015 abstract "Objective To evaluate preventive effectiveness of pocket esophagogastric anastomosis for postoperative anastomotic leak,stricture and gastroesophageal reflux disease(GERD),and investigate clinical significance of Montreal definition and classification of GERD after esophageal reconstruction.Methods Clinical data of 1 078 patients who received 2 different surgical procedures for resection of esophageal or cardiac carcinoma from June 2007 to June 2011 in our hospital were retrospectively analyzed.In the experimental group,there were 582 patients who received pocket esophagogastric anastomosis,including 403 male and 179 female patients with their age of 60.4±12.6 years.There were 399 patients with esophageal carcinoma and 183 patients with cardiac carcinoma,392 patients receiving esophagogastrostomy above the aortic arch and 190 patients receiving esophagogastrostomy below the aortic arch respectively.In the control group,there were 496 patients who received conventional end-to-side esophagogastric anastomosis,including 343 male and 153 female patients with their age of 59.2±12.8 years.There were 322 patients with esophageal carcinoma and 174 patients with cardiac carcinoma,317 patients receiving esophagogastrostomy above the aortic arch and 179 patients receiving esophagogastrostomy below the aortic arch respectively.A survey questionnaire was made on the basis of relevant diagnostic standards to investigate the incidence of postoperative anastomotic stricture and GERD of the 2 groups during follow-up.Results The incidence of postoperative anastomotic leak of the experimental group was significantly lower than that of the control group[0%(0/582)versus 1.0%(5/496),χ2=5.835,P=0.016].Patients in the experimental group had less severe GERD symptoms,and the percentage of patients who needed antacid therapy for extraesophageal symptoms of GERD of the experimental group was significantly lower than that of the control group[1.6%(33/541)versus 12.6%(57/453),χ2= 23.564,P=0.000].The incidence of anastomotic stricture of the experimental group was significantly lower than that of the control group[0.9%(5/539)versus 7.3%(34/465),χ2=25.124,P=0.000],and especially,the incidence of severe anastomotic stricture of the experimental group was significantly lower than that of the control group[0%(0/539)versus 4.7%(22/465),χ2=24.883,P=0.000].There was no statistical difference in five-year survival rate.Conclusion Pocket esophagogastric anastomosis is better than conventional end-to-side esophagogastric anastomosis for the prevention of postoperative anastomotic leak,stricture and GERD.Montreal definition and classification of GERD is suitable for the diagnosis of postoperative GERD after esophageal reconstruction." @default.
- W2368360015 created "2016-06-24" @default.
- W2368360015 creator A5057711625 @default.
- W2368360015 date "2013-01-01" @default.
- W2368360015 modified "2023-09-23" @default.
- W2368360015 title "Clinical Application of Pocket Esophagogastric Anastomosis after Esophagectomy" @default.
- W2368360015 hasPublicationYear "2013" @default.
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