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- W2368441332 abstract "Objective To investigate the effect of Dendrobium compound(DC) on islet cells injuried by streptozotocin. Methods Primarily cultured cells were treated with 0,5%,10%,20% DC drug-containing serum and 13.3 nmol / L IGF-1 respectively for 24 hours,then the cells were treated with 1.0 mmol / L STZ for 24 hours. The activity of islet cells was observed by MTT assay,the survival condition of islet cells in each group was observed by AO-EB dyeing,and the apoptosis and necrosis of cells were detected by Annexin VPI methods. Results 10%,20% DC drug-containing serum had significantly protective effect on islet cells,the activity and survival rates of cells in DC group were increased significantly compared with model group(P0.05),and the rates of apoptosis and necrosis were decreased(P0.05). The DC group and IGF-1 group showed similar protective effects. Conclusion DC drug-containing serum can protect islet cells,and reduce the cells injury induced by streptozotocin." @default.
- W2368441332 created "2016-06-24" @default.
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- W2368441332 date "2013-01-01" @default.
- W2368441332 modified "2023-09-27" @default.
- W2368441332 title "Protective Effect of Dendrobium Compound on Islet Cells Injuried by Streptozotocin" @default.
- W2368441332 hasPublicationYear "2013" @default.
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