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- W2368443374 abstract "Objective To investigate the effects of 15 ℃ seawater immersion on hemodynamic and some biochemical metabolism in hemorrhagic shock rats.Methods 24 male rats were divided into three groups:control group( n =8),hemorrhagic shock group( n =8)and hemorrhagic shock with seawater immersion group( n =8).The hemodynamic parameters,plasma lactic acid(LA),lacto dehydrogenase(LDH),phospholipase A-2(PLA-2)and the plasma and tissue MDA were measured;and H + ATPase and succinodehydrogenase(SDH) of hepatic cell and myocardium mitochondria were analyzed.Results The plasma LA,LDH,PLA-2 and the plasma and tissue MDA in hemorrhagic shock rats with seawater immersion were elevated significantly as compared with the controls and that without seawater immersion( P 0 05);whereas the hemodynamic parameters and the H + ATPase and SDH of liver cell and myocardium mitochondria were significantly lowered as compared with the controls and that without seawater immersion( P 0 05) Conclusions The shock state of hemorrhagic shock rats with 15 ℃ seawater immersion were more severe.The hymodynamics were lowered;ischemia/reperfusion injury was more severs;enzyme activity and energy metabolism of mitochondria were declined;matabolic acidosis more advanced;and PLA-2 and membrane permeability were increased." @default.
- W2368443374 created "2016-06-24" @default.
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- W2368443374 date "2000-01-01" @default.
- W2368443374 modified "2023-09-22" @default.
- W2368443374 title "Effect of seawater immersion on hemodynamic and some biochemical metabolism in hemorrhagic shock rats" @default.
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