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- W2368491640 abstract "Objective To investigate the integrons in acinetobacter and the relationship with antibiotic resistance.Methods Class 1,2and 3 integrons were detected by multiplex PCR.The homology among different strains was tested by enterobacterial repetitive intergenic consensus-PCR(ERIC-PCR) method; Restriction fragment length polymorphism(RFLP) was used to detect the integrons gene cassettes.Results 53 out of the 122 isolates contained class I integrons,and gene cassette arrays were amplified from 40 of the integrons containing isolates while four different cassette arrays were identified,which include arr-3-aacA4(24 isolates of several unrelated strains),aacC1-orfP-orfQ-aadA1a(11 isolates,probably all the same strains),(2 isolates),and dfrⅦ(1 isolates).Conclusion There are lack of correlation between integron content and carbapenem-resistance; The arrays described in China appear to be regionally loculized; and the apparent importance of the arr3 gene in a number of arrays is a distinctive feature in China.The horizontal gene transfer is clearly evident among the acinetobacter SPP.collected in this study." @default.
- W2368491640 created "2016-06-24" @default.
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- W2368491640 date "2010-01-01" @default.
- W2368491640 modified "2023-09-26" @default.
- W2368491640 title "Study on the integrons in acinetobacter and the relationship with antibiotic resistance" @default.
- W2368491640 hasPublicationYear "2010" @default.
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