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- W2368550078 abstract "This paper extracted polysaccharides from integument of Asterias amurensis and observed the curative effect of polysaccharide on the mice of alcoholic fatty liver(AFL).The method was getting the Asterias amurensis polysaccharide(AAP) by water extraction,and getting the polysaccharides by dialysis and drying.Sulfuric acid-phenol method was used for qualitative and quantitative determination of AAP in normal mice as blank control.Alcohol liver mice were divided into alcohol liver disease model group,starfish polysaccharide in low,middle dose group and high dose group(20mg/kg,40mg/kg,80mg/kg)that were observed by gavage.Alcohol(20mg/kg)was administered orally 2h after the each dose of AAP.The indexes of liver function such as levels of ALT and AST in serum were evaluated.The liver lipid and lipid super oxidation were measured.The results were that compared with the model group,the activities of ALT and AST significantly decreased(P0.05)in serum,AAP markedly decreased the contents of triglycerides(TG)(P0.05) and the content of malondialdehyde(MDA)decreased markedly(P0.05)in livertissue,the activities of superoxide dismutase(SOD)and glutathione peroxidase(GSH-PX)were higher(P0.05),in livertissue.The conclusion was that AAP could treat AFL effectively by reducing the level of liver fat and the lid peroxidation." @default.
- W2368550078 created "2016-06-24" @default.
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- W2368550078 date "2013-01-01" @default.
- W2368550078 modified "2023-09-23" @default.
- W2368550078 title "Study on Polysaccharides of Asterias amurensis about Alcoholic Fatty Liver Injury Effect in Mice" @default.
- W2368550078 hasPublicationYear "2013" @default.
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