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- W2368553556 abstract "Objective To explore the effects of Qingkailing(QKL) on apoptosis in myocardia of rats after ischemic-reperfusion.Methods Rats were divided into sham,model,DanShen and Qingkailing groups at random,8 rats in each,and were treated with medicines by sublingual vein administration respectively last 1 week.All rats were subjected to openning chest then the left anterior desending coronary arteries(LAD) were ligated for 40 min and unclamped for 120 min,at the end of,myocardial pathological changes were observed by light microscope after HE dyeing,and measure the apoptotic cells by TUNEL to observe the expressiones of caspase-3 and caspase-9 by immunohistochemistry.Results QKL downregulated the expressiones of Caspase-3,Caspase-9.Conclusion QKL have protective effects on ischemiareperfusion in rats,which may be related to downregulated the expressiones of Caspase-3,Caspase-9 during ischemia-reperfusion." @default.
- W2368553556 created "2016-06-24" @default.
- W2368553556 creator A5086877182 @default.
- W2368553556 date "2012-01-01" @default.
- W2368553556 modified "2023-09-25" @default.
- W2368553556 title "Effects of Qingkailing Injection on apoptosis related protein expression of caspase in myocardial ischemia-reperfusion injurty rats" @default.
- W2368553556 hasPublicationYear "2012" @default.
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