Matches in SemOpenAlex for { <https://semopenalex.org/work/W2368558729> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2368558729 abstract "To investigate the regulation of human α1,4-N-acetylglucosaminyltransferase (A4GNT) gene transcription,5' RACE (rapid amplification of cDNA ends) and primer extension assays were deployed to obtain the A4GNT transcription start site.A series of deletions and site-directed mutantions were constructed into the luciferase reporters based on bioinformatics analyses,and then transiently transfected into gastric cancer cells MKN45 and AGS.The luciferase assays showed that the core promoter of A4GNT gene was from-141～+ 116 bp,which contained multiple CCAAT boxes and putative binding sites for transcription factor Sp1 and ETS-1,but lacked the consensus TATA box.The Sp1 binding site(-136～-131 bp) and the forward CCAAT (-93～-89 bp) appeared to be critical for the transcriptional activity of A4GNT as shown by mutation analyses.Electrophoretic mobility shift assays (EMSA) have demonstrated the specific binding of Sp1 and NF-Y to these elements.Our additional data also suggested that the region of -1 464～-771 bp might be responsible for the cell-specific gene expression of A4GNT." @default.
- W2368558729 created "2016-06-24" @default.
- W2368558729 creator A5027977630 @default.
- W2368558729 date "2010-01-01" @default.
- W2368558729 modified "2023-09-25" @default.
- W2368558729 title "Characterization of the 5'-Flanking Region of Human α-N-acetylglucosaminyltransferase Gene" @default.
- W2368558729 hasPublicationYear "2010" @default.
- W2368558729 type Work @default.
- W2368558729 sameAs 2368558729 @default.
- W2368558729 citedByCount "0" @default.
- W2368558729 crossrefType "journal-article" @default.
- W2368558729 hasAuthorship W2368558729A5027977630 @default.
- W2368558729 hasConcept C101762097 @default.
- W2368558729 hasConcept C104317684 @default.
- W2368558729 hasConcept C105580179 @default.
- W2368558729 hasConcept C107824862 @default.
- W2368558729 hasConcept C111335760 @default.
- W2368558729 hasConcept C138885662 @default.
- W2368558729 hasConcept C150194340 @default.
- W2368558729 hasConcept C153911025 @default.
- W2368558729 hasConcept C179716448 @default.
- W2368558729 hasConcept C179926584 @default.
- W2368558729 hasConcept C183978625 @default.
- W2368558729 hasConcept C186493320 @default.
- W2368558729 hasConcept C194857396 @default.
- W2368558729 hasConcept C3662595 @default.
- W2368558729 hasConcept C41895202 @default.
- W2368558729 hasConcept C54009773 @default.
- W2368558729 hasConcept C54355233 @default.
- W2368558729 hasConcept C65888428 @default.
- W2368558729 hasConcept C86339819 @default.
- W2368558729 hasConcept C86803240 @default.
- W2368558729 hasConceptScore W2368558729C101762097 @default.
- W2368558729 hasConceptScore W2368558729C104317684 @default.
- W2368558729 hasConceptScore W2368558729C105580179 @default.
- W2368558729 hasConceptScore W2368558729C107824862 @default.
- W2368558729 hasConceptScore W2368558729C111335760 @default.
- W2368558729 hasConceptScore W2368558729C138885662 @default.
- W2368558729 hasConceptScore W2368558729C150194340 @default.
- W2368558729 hasConceptScore W2368558729C153911025 @default.
- W2368558729 hasConceptScore W2368558729C179716448 @default.
- W2368558729 hasConceptScore W2368558729C179926584 @default.
- W2368558729 hasConceptScore W2368558729C183978625 @default.
- W2368558729 hasConceptScore W2368558729C186493320 @default.
- W2368558729 hasConceptScore W2368558729C194857396 @default.
- W2368558729 hasConceptScore W2368558729C3662595 @default.
- W2368558729 hasConceptScore W2368558729C41895202 @default.
- W2368558729 hasConceptScore W2368558729C54009773 @default.
- W2368558729 hasConceptScore W2368558729C54355233 @default.
- W2368558729 hasConceptScore W2368558729C65888428 @default.
- W2368558729 hasConceptScore W2368558729C86339819 @default.
- W2368558729 hasConceptScore W2368558729C86803240 @default.
- W2368558729 hasLocation W23685587291 @default.
- W2368558729 hasOpenAccess W2368558729 @default.
- W2368558729 hasPrimaryLocation W23685587291 @default.
- W2368558729 hasRelatedWork W145757533 @default.
- W2368558729 hasRelatedWork W1501288074 @default.
- W2368558729 hasRelatedWork W1533260412 @default.
- W2368558729 hasRelatedWork W1875751464 @default.
- W2368558729 hasRelatedWork W1907858416 @default.
- W2368558729 hasRelatedWork W1963538706 @default.
- W2368558729 hasRelatedWork W1969283325 @default.
- W2368558729 hasRelatedWork W1970183355 @default.
- W2368558729 hasRelatedWork W1992266655 @default.
- W2368558729 hasRelatedWork W2004343701 @default.
- W2368558729 hasRelatedWork W2024434465 @default.
- W2368558729 hasRelatedWork W2032928625 @default.
- W2368558729 hasRelatedWork W2071039810 @default.
- W2368558729 hasRelatedWork W2076891580 @default.
- W2368558729 hasRelatedWork W2092046398 @default.
- W2368558729 hasRelatedWork W2096358451 @default.
- W2368558729 hasRelatedWork W2112838543 @default.
- W2368558729 hasRelatedWork W2117143664 @default.
- W2368558729 hasRelatedWork W2139070693 @default.
- W2368558729 hasRelatedWork W2427037858 @default.
- W2368558729 isParatext "false" @default.
- W2368558729 isRetracted "false" @default.
- W2368558729 magId "2368558729" @default.
- W2368558729 workType "article" @default.