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- W2368577035 abstract "Objective:To observe the effects on behavioral changes and hypothalamic β-endorphin of rats with bone cancer pain treated by electroacupuncture at Cuanzhu(BL2).Methods:SD rats were randomly divided into four groups: a blank group,a sham-surgery group,a electroacupuncture group and a model group,10 rats in each group.0.5 ml cells suspension of Walker256(about 2×107)were injected in tibia to establish the rat model of bone cancer pain.The changes of mechanical hyperalgesia and heat hyperalgesia were gathered at pre and post treatment.Immunohistochemistry was adopted to determine the contents of rats hypothalamic β-endorphin.Results:Compared with blank group,sham-surgery group,electroacupuncture group,mechanical hyperalgesia of model group showed a significant difference from PID9(P0.05);Compared with blank group,sham-surgery group,mechanical hyperalgesia of electroacupuncture group showed a significant difference from PID9(P0.05).Compared with blank group,sham-surgery group,electroacupuncture group,heat hyperalgesia of model group showed a significant difference from PID11(P0.05);Compared with blank group,sham-surgery group,heat hyperalgesia of electroacupuncture group showed a significant difference from PID11(P0.05).Compared with blank group and sham-surgery group,hypothalamic β-endorphin of model group showed a significant difference(P0.05);Compared with blank group,sham-surgery group,hypothalamic β-endorphin of electroacupuncture group showed a significant difference from PID9(P0.05).Conclusion:Thresholds of mechanical hyperalgesia and heat hyperalgesia were adjusted by treating with electroacupuncture at Cuanzhu(BL2).The contents of rats hypothalamic β-endorphin were restrained,which was activated by bone cancer pain." @default.
- W2368577035 created "2016-06-24" @default.
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- W2368577035 date "2013-01-01" @default.
- W2368577035 modified "2023-09-24" @default.
- W2368577035 title "Effects of Electroacupuncture on the Hypothalamic β-endorphin in Rats with Bone Cancer Pain" @default.
- W2368577035 hasPublicationYear "2013" @default.
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