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- W2368579631 abstract "To study aristolochic acid I transformation by Cunninghamella Blakesleana(AS3.910)and to make a contrast between transformation metabolites and mammalian metabolites.The multi-factors influence on transformation was investigated and the metabolites were isolated and identified by high performance liquid chromatography and mass spectrography.Many factors can influence microbial transformation,and the main metabolite was a O-demethylation compound of aristolochic acid I,which has been reported to be present in mammalian urine when aristolochic acid ingested Ⅰ.AS3.910 has the ability to catalyze O-demethylation of aristolochic acid Ⅰ specifically and it can be used as a new in vitro model to study aristolochic acid Ⅰ metabolism." @default.
- W2368579631 created "2016-06-24" @default.
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- W2368579631 date "2006-01-01" @default.
- W2368579631 modified "2023-09-24" @default.
- W2368579631 title "Microbial Transformation of Aristolochic Acid I by Cunninghamella Blakesleana" @default.
- W2368579631 hasPublicationYear "2006" @default.
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