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- W2368616459 abstract "Objective:To investigate the protective effect of Wuzi Yanzong decoction on experimental cryptorchidism mice.Method: Five-six weeks old BALB/c mice cryptorchidism was induced and divied into four groups as sham,model,low dose of Wuzi Yanzong decoction(100 mg · kg-1),high dose of Wuzi Yanzong decoction(200 mg · kg-1).At the end of the study,testis tissues were collected for detection of testes weight,sperm density,live rate,histological structure changes of testis,detection intestes glutathione peroxidase(GSH-Px),superoxide dismutase(SOD) activity and the malonyldialdehyde(MDA) content changes.Result: The Wuzi Yanzong decoction treated mice in the cryptorchid group significantly increased the mice testis weight(P0.01),sperm density(P0.05),sperm live rate(P0.01) and showed an improved histologic appearance.Wuzi Yanzong decoction treatment significantly increased the reduced SOD and GSH-Px enzyme activities(P0.05 or P0.01) and decreased the elevated tissue malondialdehyde(MDA) levels(P0.01) in testis tissues samples.Conclusion: Wuzi Yanzong decoction is a potential beneficial agent to reduce testicular damage in cryptorchid mice by decreasing oxidative stress." @default.
- W2368616459 created "2016-06-24" @default.
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- W2368616459 date "2012-01-01" @default.
- W2368616459 modified "2023-09-23" @default.
- W2368616459 title "Protective Effects of Wuzi Yanzong Decoction on Experimental Cryptorchid Mice" @default.
- W2368616459 hasPublicationYear "2012" @default.
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