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- W2368645236 abstract "Objective To investigate the expression of ACE mRNA in colorectal cancer(CRC) and analyze whether ACE mRNA expression levels correlate with clinicopathological variables in patients with CRC.Methods Tissue samples,including 31 cancerous and adjacent non-cancerous tissues were obtained from CRC patients who underwent surgical resection.The expression of ACE mRNA was quantitatively analyzed by real-time PCR.Additionally,the relationship between ACE mRNA and clinicopathological features was examined with statistical analysis.Results The expression of ACE mRNA in patients with poorly differentiated CRC was significantly higher than that in patients with moderate or well differentiated CRC.Similarly,the expression of ACE mRNA in patients with metastasis was significantly higher than that in patients without metastasis.However,no correlation was observed between ACE mRNA expression and clinical stages.Conclusion ACE may play crucial roles in CRC differentiation and metastasis." @default.
- W2368645236 created "2016-06-24" @default.
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- W2368645236 date "2011-01-01" @default.
- W2368645236 modified "2023-09-27" @default.
- W2368645236 title "Clinical study on human ACE messenger RNA expression in colorectal cancer" @default.
- W2368645236 hasPublicationYear "2011" @default.
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