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- W2368653902 abstract "Objective:To evaluate the efficacy and safety of doxazosin in treatment of essential hypertension.Methods:227 patients with seated diastolic BP(SeDBP) of 12.67～15.33kPa were randomly divided to receive 2 mg once daily doxazosin or 2 mg terazosin once daily for 2 weeks.Patients with a SeDBP higher than 12.67kPa in the end of treatment were treated with double dose of doxazosin or terazosin for another 2 weeks.The patients baseline BP,heart rate,clinical safety,and specific symptoms at the end of the first and the second 2 weeks treatment and the efficacy and safety of doxazosin was evaluated by these parameters.Results:After 4 weeks treatment,there were no significant difference in effective rate of doxazosin(67.0%,75/112) and terazosin (63.4%,64/101),no significant difference in decrease range of SeSBP/SeDBP( P 0.05).The number of patients receiving a double dose were 59 for doxazosin and 52 for terazosin.The two drugs have similar adverse reaction such as dizziness,headache,palpitation and hypodynamia,and they were tolerable and disappeared in continuous treatment.Conclusion:Essential hypertension can be effectively treated with doxazosin in once daily dose of 2～4mg." @default.
- W2368653902 created "2016-06-24" @default.
- W2368653902 creator A5014031488 @default.
- W2368653902 date "2001-01-01" @default.
- W2368653902 modified "2023-09-25" @default.
- W2368653902 title "Clinical comparison of the efficacy of doxazosin and terazosin in treatment of essential hypertension" @default.
- W2368653902 hasPublicationYear "2001" @default.
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