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- W2368670070 abstract "Objective: To observe the effects of radix astragali and sanguisuge serum on the production of transforming growth factor-β1(TGF-β1) of mesangial cell(MC) in rats.Methods: The cultured rat mesangial cells were randomly divided into nine groups including negative control,positive control,blank,high dosage of radix astragali,low dosage of radix astragali,high dosage of sanguisuge,low dosage of sanguisuge,low dosage of sanguisuge combined high dosage of astragali and low dosage of astragali combined high dosage of sanguisuge group.Five samples were included in each group.The supernatant liquid was collected and the concentrations of TGF-β1 secreted in MC were detected by ELISA.Results: TGF-β1 level increased significantly in positive controls compared with that in negative controls(P 0.01).TGF-β1 levels in medicine treated groups were significantly lower than that in blank group(P 0.01).Conclusion: The inhibition effects of sanguisuge and formula with main sanguisugem are stronger than those of radix astragali and formula with main radix astragali on TGF-β1 secretion." @default.
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- W2368670070 date "2007-01-01" @default.
- W2368670070 modified "2023-09-23" @default.
- W2368670070 title "Effects of Radix Astragali and Sanguisuge Serum on Production of Transforming Growth Factor-β1 of Mesangial Cell in Rats" @default.
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