Matches in SemOpenAlex for { <https://semopenalex.org/work/W236868617> ?p ?o ?g. }
- W236868617 endingPage "12" @default.
- W236868617 startingPage "1309" @default.
- W236868617 abstract "Cyclooxygenases catalyze the initial, rate-limiting steps of prostaglandin synthesis from arachidonic acid. Two isoforms of this enzyme exist in mammalian and avian species: COX-1 and COX-2. COX-1 is constitutively expressed and is the major isoform of gastrointestinal tissue. COX-2 is induced in response to inflammatory stimuli. COX-2 has been implicated in carcinogenesis of several neoplasms. Furthermore, COX-2 over-expression has been noted in many solid tumours and has been correlated with a worse prognosis in colorectal cancer, non-small-cell lung cancer, mesothelioma and gastric cancer. In this review, the most recent findings on the mechanisms by which COX-2 promote tumorigenesis are discussed, with particular emphasis on the studies involving spontaneous canine neoplasms." @default.
- W236868617 created "2016-06-24" @default.
- W236868617 creator A5038843491 @default.
- W236868617 creator A5043142013 @default.
- W236868617 creator A5062548989 @default.
- W236868617 creator A5086996037 @default.
- W236868617 date "2005-10-01" @default.
- W236868617 modified "2023-09-25" @default.
- W236868617 title "COX-2 overexpression in canine tumors: potential therapeutic targets in oncology." @default.
- W236868617 cites W1506163818 @default.
- W236868617 cites W1590255381 @default.
- W236868617 cites W1606427125 @default.
- W236868617 cites W1766737321 @default.
- W236868617 cites W1783009344 @default.
- W236868617 cites W1849012281 @default.
- W236868617 cites W1865550052 @default.
- W236868617 cites W1882144023 @default.
- W236868617 cites W1899590409 @default.
- W236868617 cites W1925690329 @default.
- W236868617 cites W1966825260 @default.
- W236868617 cites W1971370481 @default.
- W236868617 cites W1981100311 @default.
- W236868617 cites W1986160028 @default.
- W236868617 cites W1986616957 @default.
- W236868617 cites W2004016651 @default.
- W236868617 cites W2025997091 @default.
- W236868617 cites W2033687485 @default.
- W236868617 cites W2048654423 @default.
- W236868617 cites W2055619906 @default.
- W236868617 cites W2068806248 @default.
- W236868617 cites W2074529875 @default.
- W236868617 cites W2084815717 @default.
- W236868617 cites W2085014380 @default.
- W236868617 cites W2086512544 @default.
- W236868617 cites W2099019590 @default.
- W236868617 cites W2101492631 @default.
- W236868617 cites W2107888709 @default.
- W236868617 cites W2108627173 @default.
- W236868617 cites W2114239437 @default.
- W236868617 cites W2115014494 @default.
- W236868617 cites W2124548256 @default.
- W236868617 cites W2125215650 @default.
- W236868617 cites W2125471714 @default.
- W236868617 cites W2128075947 @default.
- W236868617 cites W2128966132 @default.
- W236868617 cites W2135236986 @default.
- W236868617 cites W2150253014 @default.
- W236868617 cites W2157294058 @default.
- W236868617 cites W2159321772 @default.
- W236868617 cites W2164920211 @default.
- W236868617 cites W2166548265 @default.
- W236868617 cites W2337738559 @default.
- W236868617 cites W2345073797 @default.
- W236868617 cites W2400262641 @default.
- W236868617 cites W2414077739 @default.
- W236868617 cites W2426052878 @default.
- W236868617 cites W2434074569 @default.
- W236868617 cites W2885344479 @default.
- W236868617 cites W2397764712 @default.
- W236868617 doi "https://doi.org/10.14670/hh-20.1309" @default.
- W236868617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16136511" @default.
- W236868617 hasPublicationYear "2005" @default.
- W236868617 type Work @default.
- W236868617 sameAs 236868617 @default.
- W236868617 citedByCount "8" @default.
- W236868617 countsByYear W2368686172012 @default.
- W236868617 countsByYear W2368686172014 @default.
- W236868617 countsByYear W2368686172015 @default.
- W236868617 countsByYear W2368686172020 @default.
- W236868617 countsByYear W2368686172023 @default.
- W236868617 crossrefType "journal-article" @default.
- W236868617 hasAuthorship W236868617A5038843491 @default.
- W236868617 hasAuthorship W236868617A5043142013 @default.
- W236868617 hasAuthorship W236868617A5062548989 @default.
- W236868617 hasAuthorship W236868617A5086996037 @default.
- W236868617 hasConcept C104317684 @default.
- W236868617 hasConcept C121608353 @default.
- W236868617 hasConcept C126322002 @default.
- W236868617 hasConcept C142724271 @default.
- W236868617 hasConcept C143998085 @default.
- W236868617 hasConcept C181199279 @default.
- W236868617 hasConcept C2776256026 @default.
- W236868617 hasConcept C2777407522 @default.
- W236868617 hasConcept C2778078955 @default.
- W236868617 hasConcept C502942594 @default.
- W236868617 hasConcept C526805850 @default.
- W236868617 hasConcept C53345823 @default.
- W236868617 hasConcept C55493867 @default.
- W236868617 hasConcept C555283112 @default.
- W236868617 hasConcept C71924100 @default.
- W236868617 hasConcept C86803240 @default.
- W236868617 hasConceptScore W236868617C104317684 @default.
- W236868617 hasConceptScore W236868617C121608353 @default.
- W236868617 hasConceptScore W236868617C126322002 @default.
- W236868617 hasConceptScore W236868617C142724271 @default.
- W236868617 hasConceptScore W236868617C143998085 @default.
- W236868617 hasConceptScore W236868617C181199279 @default.
- W236868617 hasConceptScore W236868617C2776256026 @default.