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- W2368698869 abstract "OBJECTIVE To observe the alteration of the hepatic CYP450 content in rats after oral administration of the different processed Fructus schisandrae Chinensis.METHODS The rats were given orally the different doses of the aqueous and alcohol extracts of the crude and processed schisandrae for six days.Then the liver microsomes were prepared,and the liver coefficient,the protein content and P450 level were determined.RESULTS Compared with the group of physiological saline,the high and low dose of aqueous of the different processed schisandrae can inhabit the liver coefficient.The protein content were enhanced significantly in the liver microsomes with the middle and high dose of the alcohol extracts and aqueous of the different processed schisandrae with compare of physiological saline.The levels of CYP450 were enhanced significantly with the middle dose of alcohol extracts and high dose of the vinegar products and the alcohol extracts of crude products.CONCLUSION Fructus schisandra Chinensis.made by vinegar showed induction effect on hepatic protein and CYP450 level in rats." @default.
- W2368698869 created "2016-06-24" @default.
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- W2368698869 date "2011-01-01" @default.
- W2368698869 modified "2023-09-23" @default.
- W2368698869 title "Induction effects of the different processed Fructus schisandrae Chinensis on the hepatic microsomal cytochrome P450 in rats" @default.
- W2368698869 hasPublicationYear "2011" @default.
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