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- W2368705428 abstract "Objective:To compare the treatment effects of rosiglit azone and me-tformin on endocrine and metabolism in polycystic ovarian syndrome's(PCOS)patients with insulin resistance.Methods:45 PCOS's patients were randomly divided into two groups and each group was given rosiglitazone or metformin for 4 months.Changes of body mass index(BMI),endocrinal hormone and blood lipids were analyzed before and after treatment.Results:There was remarkably decrease in the level of testosterone(T),luteinizing hormone(LH), LH/FSH,fasting insulin(FINS),2 h insulin(2hINS),2 h plasma glucose(2 hPG)and Homa IR between two groups after treat ment.But BMI was decreased after using metformin,and the level of T,FINS,2 hINS,homa IR were more efficiently decreased after using rosiglitazone.Conclusion:Rosiglitazone,which had better effects on improving insulin resistance and glucose metabolism,affects more conspicuously insulin resistance and hyper insulinemia;While mefformin,which can reduces weight,is suitable for fat PCOS patients with not serious insulin resistance." @default.
- W2368705428 created "2016-06-24" @default.
- W2368705428 creator A5082096321 @default.
- W2368705428 date "2010-01-01" @default.
- W2368705428 modified "2023-09-26" @default.
- W2368705428 title "Effects of metformin and rosiglitazone in the treatment of polycystic ovarian syndrome with insulin resistance" @default.
- W2368705428 hasPublicationYear "2010" @default.
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