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- W2368753209 abstract "Objective To establish an experimental model of gentamicin dose dependent damage to the hair cells in vestibular organ cultured. Methods Microdissection of vestibular end-organs, vestibular organotypic culture, and vestibular histological techniques were used to e-valuate the ototoxic effects of gentamicin on cultured vestibular end-organ in vitro. Results Gentamicin destroyed vestibular hair cells in a dose dependent manner. The hair cells in the top of the crista and the striola of macula in saccule and utricle were more sensetive to gentamicin oto-toxicity than those in its marginal region. Conclusion It is suggested that the ototoxic effects of gentamicin to cultured vestibular end-organs are similar to that occured in vivo." @default.
- W2368753209 created "2016-06-24" @default.
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- W2368753209 date "2003-01-01" @default.
- W2368753209 modified "2023-09-23" @default.
- W2368753209 title "Gentamicin Ototoxicity to the vestibular end-organ of mouse cultured in vitro" @default.
- W2368753209 hasPublicationYear "2003" @default.
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