Matches in SemOpenAlex for { <https://semopenalex.org/work/W2368754684> ?p ?o ?g. }
Showing items 1 to 79 of
79
with 100 items per page.
- W2368754684 abstract "Objective To investigate the effects of recombinant human growth hormone(rhGH)on proliferation of alveolar type Ⅱ cells and expression of Bcl-2 and Bax protein in rats with smoke inhalation injury.Methods Seventy Sprague-Dawley rats weighting 160-180 g were randomly divided into three groups:groupⅠwas normal controls(10);group Ⅱwas smoke inhalation(30);groupⅢwas smoke inhalation combined with rhGH administration(30).The animals in group Ⅱ and Ⅲwere sacrificed at 6,10,14 days after smoke inhalation injury.rhGH(1.33 U/kg)was administered subcutaneously in rhGH group for 7 days.The rats were killed and the lungs were immediately removed separately at 6,10,14 days,the proliferation of AT Ⅱ cells and expression of Bcl-2 and Bax protein were observed by immunohistochemical method.Results Morphological studies found that there were more proliferated AT Ⅱcells in group Ⅲthan group Ⅱ.Normal rats had no expression of Bcl-2 and Bax protein.In group Ⅱ,the expression of Bcl-2 and Bax protein was all increased after inhalation injury.The expression of Bcl-2 protein increased but Bax protein decreased from the beginning of 6 days treated with rhGH in the treatment groupⅢ,the differences were statistically significant.Conclusions rhGH can stimulate the proliferation of AT Ⅱ cells,and up-regulate the expression of Bcl-2 protein,down-regulate the expression of Bax protein and change the ratio of Bcl-2/Bax to decrease apoptosis of the lung cell." @default.
- W2368754684 created "2016-06-24" @default.
- W2368754684 creator A5054904910 @default.
- W2368754684 date "2008-01-01" @default.
- W2368754684 modified "2023-09-25" @default.
- W2368754684 title "Effects of recombinant human growth hormone on proliferation of alveolar type II cells and expression of Bcl-2 and Bax protein in rats with smoke inhalation injury" @default.
- W2368754684 hasPublicationYear "2008" @default.
- W2368754684 type Work @default.
- W2368754684 sameAs 2368754684 @default.
- W2368754684 citedByCount "0" @default.
- W2368754684 crossrefType "journal-article" @default.
- W2368754684 hasAuthorship W2368754684A5054904910 @default.
- W2368754684 hasConcept C104317684 @default.
- W2368754684 hasConcept C12519072 @default.
- W2368754684 hasConcept C126322002 @default.
- W2368754684 hasConcept C134018914 @default.
- W2368754684 hasConcept C16685009 @default.
- W2368754684 hasConcept C190283241 @default.
- W2368754684 hasConcept C203014093 @default.
- W2368754684 hasConcept C204232928 @default.
- W2368754684 hasConcept C2776954882 @default.
- W2368754684 hasConcept C2777390754 @default.
- W2368754684 hasConcept C2777714996 @default.
- W2368754684 hasConcept C2780362710 @default.
- W2368754684 hasConcept C2909544034 @default.
- W2368754684 hasConcept C31573885 @default.
- W2368754684 hasConcept C42219234 @default.
- W2368754684 hasConcept C55493867 @default.
- W2368754684 hasConcept C62112901 @default.
- W2368754684 hasConcept C6856738 @default.
- W2368754684 hasConcept C71924100 @default.
- W2368754684 hasConcept C86803240 @default.
- W2368754684 hasConceptScore W2368754684C104317684 @default.
- W2368754684 hasConceptScore W2368754684C12519072 @default.
- W2368754684 hasConceptScore W2368754684C126322002 @default.
- W2368754684 hasConceptScore W2368754684C134018914 @default.
- W2368754684 hasConceptScore W2368754684C16685009 @default.
- W2368754684 hasConceptScore W2368754684C190283241 @default.
- W2368754684 hasConceptScore W2368754684C203014093 @default.
- W2368754684 hasConceptScore W2368754684C204232928 @default.
- W2368754684 hasConceptScore W2368754684C2776954882 @default.
- W2368754684 hasConceptScore W2368754684C2777390754 @default.
- W2368754684 hasConceptScore W2368754684C2777714996 @default.
- W2368754684 hasConceptScore W2368754684C2780362710 @default.
- W2368754684 hasConceptScore W2368754684C2909544034 @default.
- W2368754684 hasConceptScore W2368754684C31573885 @default.
- W2368754684 hasConceptScore W2368754684C42219234 @default.
- W2368754684 hasConceptScore W2368754684C55493867 @default.
- W2368754684 hasConceptScore W2368754684C62112901 @default.
- W2368754684 hasConceptScore W2368754684C6856738 @default.
- W2368754684 hasConceptScore W2368754684C71924100 @default.
- W2368754684 hasConceptScore W2368754684C86803240 @default.
- W2368754684 hasLocation W23687546841 @default.
- W2368754684 hasOpenAccess W2368754684 @default.
- W2368754684 hasPrimaryLocation W23687546841 @default.
- W2368754684 hasRelatedWork W1507239708 @default.
- W2368754684 hasRelatedWork W1772511103 @default.
- W2368754684 hasRelatedWork W2284265706 @default.
- W2368754684 hasRelatedWork W2350575684 @default.
- W2368754684 hasRelatedWork W2365746137 @default.
- W2368754684 hasRelatedWork W2375230134 @default.
- W2368754684 hasRelatedWork W2392535370 @default.
- W2368754684 hasRelatedWork W2402183039 @default.
- W2368754684 hasRelatedWork W2411780338 @default.
- W2368754684 hasRelatedWork W2898435751 @default.
- W2368754684 hasRelatedWork W2946892573 @default.
- W2368754684 hasRelatedWork W3029841120 @default.
- W2368754684 hasRelatedWork W3030257585 @default.
- W2368754684 hasRelatedWork W3030480377 @default.
- W2368754684 hasRelatedWork W3030888874 @default.
- W2368754684 hasRelatedWork W3030997800 @default.
- W2368754684 hasRelatedWork W3032003078 @default.
- W2368754684 hasRelatedWork W3032533551 @default.
- W2368754684 hasRelatedWork W3082281988 @default.
- W2368754684 hasRelatedWork W3151001654 @default.
- W2368754684 isParatext "false" @default.
- W2368754684 isRetracted "false" @default.
- W2368754684 magId "2368754684" @default.
- W2368754684 workType "article" @default.