Matches in SemOpenAlex for { <https://semopenalex.org/work/W2368756893> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2368756893 endingPage "90" @default.
- W2368756893 startingPage "987" @default.
- W2368756893 abstract "The aim of this study was to explore the clinical effect and toxicity of bortezomib combined with methylprednisolone in treatment of relapsed or refractory multiple myeloma (MM). Clinical data of 33 patients (23 male, 10 female; aged from 38 to 85 years old) were analyzed retrospectively. The median diagnosis time was 25 (2 - 120) months. 33 patients received bortezomib (0.9 - 1.1) mg/m(2) on days 1, 4, 8, 11, in combination with methylprednisolone 40 mg/d (4 cases), 80mg/d (13 cases), 120 mg/d (2 cases), 200 mg/d (9 cases), 300 mg/d (5 cases) respectively. The median follow-up time was 10(3-60) months. The used therapy courses were 1 - 8 (mean 4 courses). The results indicated that 24 cases showed the response of different degree, the overall response rate (ORR) was 72.7% (24/33). 32 patients received ≥ 2 therapy courses, and ORR was 71.9% (23/32). 16 patients received 4 therapy courses, and ORR was 93.8% (15/16 cases). 7 patients received 6 therapy courses and the ORR was 100% (7/7 cases). Main side-effects were thrombocytopenia, infection and peripheral neuropathy. The median survival time was 41.5 (2 - 120) months and the 2-year, 3-year and 5-year overall survival rate were 80%, 59.1% and 21.1%, respectively. It is concluded that bortezomib combined with methylprednisolone is an effective therapy with higher response rate, and safe in treatment of relapsed or refractory multiple myeloma." @default.
- W2368756893 created "2016-06-24" @default.
- W2368756893 creator A5001443657 @default.
- W2368756893 creator A5002231070 @default.
- W2368756893 creator A5002806534 @default.
- W2368756893 creator A5022526821 @default.
- W2368756893 creator A5048761231 @default.
- W2368756893 creator A5091598527 @default.
- W2368756893 date "2011-08-01" @default.
- W2368756893 modified "2023-09-26" @default.
- W2368756893 title "[Effects of bortezomib combined with methylprednisolone in treatment of 33 cases of relapsed or refractory multiple myeloma]." @default.
- W2368756893 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21867630" @default.
- W2368756893 hasPublicationYear "2011" @default.
- W2368756893 type Work @default.
- W2368756893 sameAs 2368756893 @default.
- W2368756893 citedByCount "0" @default.
- W2368756893 crossrefType "journal-article" @default.
- W2368756893 hasAuthorship W2368756893A5001443657 @default.
- W2368756893 hasAuthorship W2368756893A5002231070 @default.
- W2368756893 hasAuthorship W2368756893A5002806534 @default.
- W2368756893 hasAuthorship W2368756893A5022526821 @default.
- W2368756893 hasAuthorship W2368756893A5048761231 @default.
- W2368756893 hasAuthorship W2368756893A5091598527 @default.
- W2368756893 hasConcept C121332964 @default.
- W2368756893 hasConcept C126322002 @default.
- W2368756893 hasConcept C141071460 @default.
- W2368756893 hasConcept C142424586 @default.
- W2368756893 hasConcept C2776364478 @default.
- W2368756893 hasConcept C2777478702 @default.
- W2368756893 hasConcept C2780372218 @default.
- W2368756893 hasConcept C71924100 @default.
- W2368756893 hasConcept C87355193 @default.
- W2368756893 hasConcept C90924648 @default.
- W2368756893 hasConceptScore W2368756893C121332964 @default.
- W2368756893 hasConceptScore W2368756893C126322002 @default.
- W2368756893 hasConceptScore W2368756893C141071460 @default.
- W2368756893 hasConceptScore W2368756893C142424586 @default.
- W2368756893 hasConceptScore W2368756893C2776364478 @default.
- W2368756893 hasConceptScore W2368756893C2777478702 @default.
- W2368756893 hasConceptScore W2368756893C2780372218 @default.
- W2368756893 hasConceptScore W2368756893C71924100 @default.
- W2368756893 hasConceptScore W2368756893C87355193 @default.
- W2368756893 hasConceptScore W2368756893C90924648 @default.
- W2368756893 hasIssue "4" @default.
- W2368756893 hasLocation W23687568931 @default.
- W2368756893 hasOpenAccess W2368756893 @default.
- W2368756893 hasPrimaryLocation W23687568931 @default.
- W2368756893 hasRelatedWork W14747713 @default.
- W2368756893 hasRelatedWork W1999964913 @default.
- W2368756893 hasRelatedWork W2097007321 @default.
- W2368756893 hasRelatedWork W2340210278 @default.
- W2368756893 hasRelatedWork W2346817266 @default.
- W2368756893 hasRelatedWork W2349895913 @default.
- W2368756893 hasRelatedWork W2350480662 @default.
- W2368756893 hasRelatedWork W2353532459 @default.
- W2368756893 hasRelatedWork W2363734051 @default.
- W2368756893 hasRelatedWork W2389251362 @default.
- W2368756893 hasRelatedWork W2563955350 @default.
- W2368756893 hasRelatedWork W2569232645 @default.
- W2368756893 hasRelatedWork W2570467653 @default.
- W2368756893 hasRelatedWork W2570571228 @default.
- W2368756893 hasRelatedWork W2588946684 @default.
- W2368756893 hasRelatedWork W2982715530 @default.
- W2368756893 hasRelatedWork W3031147360 @default.
- W2368756893 hasRelatedWork W3032465158 @default.
- W2368756893 hasRelatedWork W3657330 @default.
- W2368756893 hasRelatedWork W3166425146 @default.
- W2368756893 hasVolume "19" @default.
- W2368756893 isParatext "false" @default.
- W2368756893 isRetracted "false" @default.
- W2368756893 magId "2368756893" @default.
- W2368756893 workType "article" @default.